Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27370347 | 0.96 | HPGD (0.57) | SNCACYP3A4HPGDNPC1RAB9A | |
| SCHEMBL9063776 | 0.95 | SNCA (0.54) | SNCACYP3A4HPGDNPC1RAB9A | |
| SCHEMBL175786 | 0.90 | SNCA (0.67) | SNCACYP3A4HPGDKDM4ELMNA | |
| SCHEMBL17386391 | 0.85 | SNCA (0.61) | SNCACYP3A4HPGDKDM4ELMNA | |
| SCHEMBL461801 | 0.85 | SNCA (0.61) | SNCACYP3A4KDM4ELMNAALDH1A1 | |
| SCHEMBL17775085 | 0.84 | SNCA (0.56) | SNCACYP3A4NPC1RAB9ALMNA | |
| SCHEMBL175787 | 0.83 | SNCA (0.59) | SNCACYP3A4ALDH1A1TSHRHSD17B10 | |
| SCHEMBL31182 | 0.83 | SNCA (0.59) | SNCACYP3A4HPGDNPC1RAB9A | |
| SCHEMBL5675836 | 0.83 | SNCA (0.59) | SNCACYP3A4HPGDKDM4ELMNA | |
| SCHEMBL7090148 | 0.83 | HPGD (0.53) | HPGDNPC1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004611-A1 | PROCESS FOR PREPARING RETINOID COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2008-12-24 | — | — | EP | claimed |
| WO-2007113122-A1 | PROCESS FOR PREPARING RETINOID COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-10-11 | — | — | WO | claimed |
| US-20070232810-A1 | Process for preparing retinoid compounds | ROCHE PALO ALTO LLC | 2007-10-04 | — | — | US | claimed |
| EP-1791824-A1 | RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER | Showa Denko K.K. (JP) | 2007-06-06 | — | — | EP | claimed |
| WO-2006033438-A1 | RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER | SHOWA DENKO K.K. (JP) | 2006-03-30 | — | — | WO | claimed |
| US-20250296915-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2025-09-25 | — | — | US | disclosed |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
| EP-4146634-A1 | SYNTHESIS OF VINYL CYCLOBUTYL INTERMEDIATES | Amgen Inc. (US) | 2023-03-15 | — | — | EP | disclosed |
| CN-113165257-A | Apparatus for producing cured resin film and method for producing cured resin film | 昭和电工株式会社 | 2021-07-23 | — | — | CN | disclosed |
| US-20190202813-A1 | Process for preparing 4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro-phenyl)tetrahydrofuran-3-yl)methoxy)-3-methylphenyl)piperazin-1-yl)-N-((1S,2S)-2-hydroxycyclohexyl)benzamide or a pharmaceutically acceptable salt thereof | PULMOCIDE LIMITED (GB) | 2019-07-04 | — | — | US | disclosed |
| US-10280155-B2 | Process for preparing 4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro-phenyl)tetrahydrofuran-3-yl)methoxy)-3-methylphenyl)piperazin-1-yl)-N-((1S,2S)-2-hydroxycyclohexyl) benzamide or a pharmaceutically acceptable salt thereof | PULMOCIDE LIMITED (GB) | 2019-05-07 | — | — | US | disclosed |
| US-20180251453-A1 | COMPOUNDS | PULMOCIDE LIMITED (GB) | 2018-09-06 | — | — | US | disclosed |
| WO-2007086607-A2 | RADICALLY POLYMERIZABLE COMPOUND HAVING A CYCLIC DITHIOCARBONATE GROUP | SHOWA DENKO K.K. (JP) | 2007-08-02 | — | — | WO | disclosed |
| EP-1791824-A1 | RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER | Showa Denko K.K. (JP) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006033438-A1 | RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER | SHOWA DENKO K.K. (JP) | 2006-03-30 | — | — | WO | disclosed |
| CN-1466598-A | Plastic lens composition, plastic lens and method for producing the plastic lens | �Ѻ͵繤��ʽ���� | 2004-01-07 | — | — | CN | disclosed |
| WO-2003010566-A2 | PLASTIC LENS MATERIAL, PLASTIC LENS COMPOSITION, PLASTIC LENS OBTAINED BY CURING THE COMPOSITION AND PROCESS FOR PRODUCING THE PLASTIC LENS | SHOWA DENKO K. K. (JP) | 2003-02-06 | — | — | WO | disclosed |
| US-6319948-B2 | PREVENTION AND/OR MINIMIZATION OF SURGICAL ADHESION FORMATION BY ADMINISTERING CERTAIN SUBSTITUTED (5,6)-DIHYDRONAPHTHALENYL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2001-11-20 | — | — | US | disclosed |
| US-20010003780-A1 | Retinoid antagonists and uses thereof | TRAMPOSCH KENNETH M (US) | 2001-06-14 | — | — | US | disclosed |
| WO-1998046228-A1 | RETINOID ANTAGONISTS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10280155-B2 | Process for preparing 4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro-phenyl)tetrahydrofuran-3-yl)methoxy)-3-methylphenyl)piperazin-1-yl)-N-((1S,2S)-2-hydroxycyclohexyl) benzamide or a pharmaceutically acceptable salt thereof | HRH4, HRH1, CYP2S1 | SNCA 793/4885CYP3A4 13/4885HPGD 1540/4885 |
| US-20250296915-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | SNCA 2855/4885CYP3A4 4395/4885HPGD 3826/4885 |
| US-20010003780-A1 | Retinoid antagonists and uses thereof | RARA, RARB, RARG | SNCA 4557/4885CYP3A4 3104/4885HPGD 318/4885 |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | SNCA 2070/4885CYP3A4 4397/4885HPGD 2952/4885 |
| US-20190202813-A1 | Process for preparing 4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro-phenyl)tetrahydrofuran-3-yl)methoxy)-3-methylphenyl)piperazin-1-yl)-N-((1S,2S)-2-hydroxycyclohexyl)benzamide or a pharmaceutically acceptable salt thereof | HRH4, HRH1, CYP2S1 | SNCA 793/4885CYP3A4 13/4885HPGD 1540/4885 |
| US-20180251453-A1 | COMPOUNDS | MYC, DPM1, ERG28 | SNCA 3302/4885CYP3A4 212/4885HPGD 1465/4885 |
| US-20070232810-A1 | Process for preparing retinoid compounds | RARB, RARG, RARA | SNCA 4568/4885CYP3A4 252/4885HPGD 658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.