SCHEMBL4433763

SCHEMBL4433763

CC1CCNc2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 4/20 0.39
HTR2A P28223 1/20 0.39
HTR2B P41595 1/20 0.39
BCHE P06276 1/20 0.38
AR P10275 2/20 0.36
PGR P06401 1/20 0.35
HTR5A P47898 3/20 0.35
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34
F12 P00748 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12350357 1.00 HTR2C (0.39) HTR2CHTR2AHTR2BBCHEAR
SCHEMBL29641546 1.00 HTR2C (0.39) HTR2CHTR2AHTR2BBCHEAR
SCHEMBL12350365 1.00 HTR2C (0.39) HTR2CHTR2AHTR2BBCHEAR
SCHEMBL5467478 0.88 HTR2C (0.37) HTR2CHTR2AHTR2BBCHEHTR5A
SCHEMBL25786676 0.86 BCHE (0.39) HTR2CHTR2AHTR2BBCHEHTR5A
SCHEMBL25604373 0.85 BCHE (0.40) HTR2CHTR2AHTR2BBCHEHTR5A
SCHEMBL5749290 0.78 HTR2C (0.46) HTR2CHTR2AHTR2BARHTR5A
SCHEMBL18883053 0.78 HTR2C (0.46) HTR2CHTR2AHTR2BARHTR5A
SCHEMBL548964 0.78 HTR2C (0.46) HTR2CHTR2AHTR2BARHTR5A
SCHEMBL13372443 0.78 HTR2C (0.46) HTR2CHTR2AHTR2BARHTR5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109529907-B Nitrogen-doped carbon material supported cobalt catalyst, preparation method thereof and application thereof in catalytic oxidation of N-heterocyclic compound 中南民族大学 2021-10-15 CN claimed
CN-111943134-A Room-temperature dehydrogenation reaction system of photocatalytic organic liquid hydrogen storage material and preparation method and application thereof 中国科学院理化技术研究所 2020-11-17 CN claimed
CN-109529907-A A kind of nitrogen-doped carbon material load cobalt catalyst and preparation method thereof and the application in N- heterocyclic compound catalysis oxidation 中南民族大学 2019-03-29 CN claimed
CN-107141252-A A kind of method that hydrotalcite-like materials are catalyzed nitrogen-containing heterocycle compound oxidative dehydrogenation 常州大学 2017-09-08 CN claimed
CN-104649854-A Cheap and efficient preparation method of aryl halides UNIV BEIJING 2015-05-27 CN claimed
US-7101869-B2 2,4-diaminopyrimidine compounds useful as immunosuppressants PFIZER INC. (US) 2006-09-05 US claimed
EP-1242403-B1 2,4-DIAMINOPYRIMIDINE COMPOUNDS USFUL AS IMMUNOSUPPRESSANTS PFIZER PROD INC (US) 2006-01-04 EP claimed
US-20030191307-A1 2,4-Diaminopyrimidine compounds useful as immunosuppressants BLUMENKOPF TODD A (US) 2003-10-09 US claimed
CN-122059875-A Method for synthesizing quinoline compound by catalytic dehydrogenation of tetrahydroquinoline compound 西安石油大学 2026-05-19 CN disclosed
EP-3630770-B1 PYRAZOLO[3,4-B]PYRAZINE DERIVATIVES AS SHP2 PHOSPHATASE INHIBITORS RELAY THERAPEUTICS INC (US) 2024-08-28 EP disclosed
CN-117143015-A Synthesis method of tetrahydroquinoline 温州大学新材料与产业技术研究院 2023-12-01 CN disclosed
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2023-10-26 US disclosed
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2023-10-26 US disclosed
US-20230331663-A1 SMALL MOLECULE NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATORS THE CLEVELAND CLINIC FOUNDATION 2023-10-19 US disclosed
US-4739063-A USING CATALYST PHILLIPS PETROLEUM COMPANY (US) 1988-04-19 US disclosed
US-4739064-A USING GROUP 8 METAL CATALYSTS AND REACTION MODIFIERS PHILLIPS PETROLEUM COMPANY (US) 1988-04-19 US disclosed
EP-0198264-A2 Carbamoyl imidazoles NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-10-22 EP disclosed
US-4587341-A BACTERICIDES BURROUGHS WELLCOME CO. (US) 1986-05-06 US disclosed
EP-0096214-A1 Antibacterial pyrimidine compounds THE WELLCOME FOUNDATION LIMITED (GB) 1983-12-21 EP disclosed
US-4015005-A TRANQUILIZERS, SLEEP INDUCERS, CNS DEPRESSANTS SANDOZ, INC. (US) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030191307-A1 2,4-Diaminopyrimidine compounds useful as immunosuppressants CCR1, AOC1, NOD1 HTR2C 2420/4885HTR2A 3872/4885HTR2B 3518/4885
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 IKZF1, IKZF3, IKZF2 HTR2C 3544/4885HTR2A 3868/4885HTR2B 4767/4885
US-20230331663-A1 SMALL MOLECULE NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATORS NQO1, NADK, CD38 HTR2C 4666/4885HTR2A 3716/4885HTR2B 4089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.