⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1447597 | 0.96 | — | — | |
| SCHEMBL2250645 | 0.96 | CA1 (0.32) | — | |
| SCHEMBL5553 | 0.96 | — | — | |
| SCHEMBL645663 | 0.92 | — | — | |
| SCHEMBL608110 | 0.84 | — | — | |
| SCHEMBL20262877 | 0.73 | L3MBTL3 (0.44) | — | |
| SCHEMBL357819 | 0.72 | RAB9A (0.34) | — | |
| SCHEMBL3431740 | 0.72 | — | — | |
| SCHEMBL13292040 | 0.72 | — | — | |
| SCHEMBL213233 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2906 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029739-B2 | SHP2 inhibitor and use thereof | KANAPH THERAPEUTICS INC. (KR) | 2024-07-09 | — | — | US | claimed |
| US-20240189306-A1 | SHP2 INHIBITOR AND USE THEREOF | KANAPH THERAPEUTICS INC. (KR) | 2024-06-13 | — | — | US | claimed |
| CN-112437773-B | Catechol derivatives or salts thereof, process for preparing the same and pharmaceutical compositions containing the same | 六合医药科技有限公司 | 2024-06-11 | — | — | CN | claimed |
| WO-2024104425-A1 | KRAS INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 广东东阳光药业股份有限公司 | 2024-05-23 | — | — | WO | claimed |
| EP-4370522-A1 | ALKYLIDENE DERIVATIVES AS KRAS INHIBITORS | Nikang Therapeutics, Inc. (US) | 2024-05-22 | — | — | EP | claimed |
| CN-118047801-A | KRAS inhibitor compound, pharmaceutical composition and application thereof | 广东东阳光药业股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| EP-4368625-A1 | SHP2 INHIBITOR AND USE THEREOF | Kanaph Therapeutics Inc. (KR) | 2024-05-15 | — | — | EP | claimed |
| CN-117980310-A | Alkylene derivatives as KRAS inhibitors | 尼坎治疗公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117916242-A | SHP2 inhibitors and uses thereof | 治纳辅医药科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| EP-3750894-B1 | UREA-SUBSTITUTED AROMATIC RING-LINKED DIOXAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2024-04-03 | — | — | EP | claimed |
| US-4339448-A | Imidazole-copper complex compounds and fungicides containing them | BASF AKTIENGESELLSCHAFT (DE) | 1982-07-13 | — | — | US | claimed |
| US-4129734-A | HERBICIDE | THE DOW CHEMICAL COMPANY (US) | 1978-12-12 | — | — | US | claimed |
| US-4129733-A | HERBICIDE | THE DOW CHEMICAL COMPANY (US) | 1978-12-12 | — | — | US | claimed |
| US-4104380-A | Dibenzyl glycolic acid derivatives | WARNER-LAMBERT COMPANY (US) | 1978-08-01 | — | — | US | claimed |
| US-4093805-A | ANTIDEPRESSANT AND ANTIANXIETY ACTIVITY | THE DOW CHEMICAL COMPANY (US) | 1978-06-06 | — | — | US | claimed |
| US-4085278-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1978-04-18 | — | — | US | claimed |
| US-4085279-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1978-04-18 | — | — | US | claimed |
| US-4076937-A | Dibenzyl glycolic acid derivatives | WARNER-LAMBERT COMPANY (US) | 1978-02-28 | — | — | US | claimed |
| US-3989507-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1976-11-02 | — | — | US | claimed |
| US-3959270-A | DIURETICS, ANTIHYPERTENSIVE, ANTIULCER, ANTIINFLAMMATORY, SEDATIVES, ANALGESICS | DELALANDE S.A. (FR) | 1976-05-25 | — | — | US | claimed |