Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 7/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426779 | 0.95 | FPR1 (0.37) | FPR1FPR2CASP1CTSAKMT2A | |
| SCHEMBL4436791 | 0.93 | KMT2A (0.36) | FPR1FPR2CASP1CTSAKMT2A | |
| SCHEMBL4435242 | 0.90 | CASP1 (0.37) | FPR1FPR2CASP1CTSAGPR88 | |
| SCHEMBL6759870 | 0.89 | FFAR1 (0.36) | FPR1FPR2CASP1CTSAKMT2A | |
| SCHEMBL4434290 | 0.89 | FPR1 (0.39) | FPR1CASP1CTSAKMT2AFFAR1 | |
| SCHEMBL6759875 | 0.88 | FPR1 (0.43) | FPR1FPR2CASP1KMT2AFFAR1 | |
| SCHEMBL4427172 | 0.88 | CASP1 (0.43) | FPR1FPR2CASP1KMT2AGPR88 | |
| SCHEMBL4424304 | 0.88 | FPR1 (0.44) | FPR1FPR2CASP1FFAR1SMN1; SMN2 | |
| SCHEMBL4427169 | 0.88 | FPR1 (0.37) | FPR1FPR2CASP1KMT2AFFAR1 | |
| SCHEMBL4426944 | 0.86 | FPR1 (0.39) | FPR1FPR2CASP1CTSAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213288-B1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1213288-A1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-06-12 | — | — | EP | disclosed |