Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3335231 | 0.80 | MGLL (0.50) | MGLLTHRBMEN1ALDH1A1KMT2A | |
| SCHEMBL25381206 | 0.72 | MGLL (0.56) | MGLLTHRBMEN1KMT2ATP53 | |
| SCHEMBL31414907 | 0.72 | MGLL (0.56) | MGLLTHRBMEN1KMT2AFAAH | |
| SCHEMBL31715409 | 0.72 | ALDH1A1 (0.57) | MGLLALDH1A1EPHX1FAAHTRPV1 | |
| SCHEMBL4433141 | 0.70 | MGLL (0.52) | MGLLTHRBMEN1ALDH1A1KMT2A | |
| SCHEMBL31715640 | 0.70 | MGLL (0.56) | MGLLALDH1A1FAAHTRPV1CYP1A2 | |
| SCHEMBL31715825 | 0.69 | MGLL (0.59) | MGLLALDH1A1FAAHTRPV1L3MBTL1 | |
| SCHEMBL31414904 | 0.69 | MGLL (0.53) | MGLLTHRBALDH1A1KMT2ATP53 | |
| SCHEMBL22370754 | 0.69 | MGLL (0.47) | MGLLTHRBMEN1ALDH1A1KMT2A | |
| SCHEMBL18703462 | 0.68 | MGLL (0.78) | MGLLMEN1KMT2AFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118052-A2 | NOVEL PRODRUGS | Sun Pharma Advanced Research Company Ltd (IN) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008111096-A2 | NOVEL PRODRUGS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2008-09-18 | — | — | WO | disclosed |