SCHEMBL4434256

SCHEMBL4434256

Cc1cc2c(cc1C(C)(C)C)-c1cc(C(C)(C)C)c(C)cc1C2[Zr](C1=CC=CC1)=C(c1ccccc1)c1cccc(C(F)(F)F)c1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
CES2 O00748 1/20 0.32
RBP4 P02753 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
TAS1R2 Q8TE23 1/20 0.31
KMT2A Q03164 2/20 0.30
MEN1 O00255 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14735582 0.97 CES2 (0.34) GAACES2RBP4TAS1R3TAS1R1
Hydrochloric Acid SCHEMBL811910 0.96 CES2 (0.33) GAACES2RBP4TAS1R3TAS1R1
SCHEMBL4429943 0.94 CES2 (0.34) GAACES2RBP4TAS1R3TAS1R1
SCHEMBL14735793 0.92 CES2 (0.36) CES2RBP4TAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL811766 0.91 CES2 (0.36) CES2RBP4TAS1R3TAS1R1TAS1R2
SCHEMBL4434269 0.90 ALDH1A1 (0.35) CES2RBP4TAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL812170 0.90
SCHEMBL14735586 0.89 ALDH1A1 (0.35) CES2RBP4TAS1R3TAS1R1TAS1R2
SCHEMBL4952125 0.89 CNR2 (0.32)
SCHEMBL18695284 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11492471-B2 Polypropylene resin composition and monolayer and multilayer film MITSUI CHEMICALS, INC. (JP) 2022-11-08 US disclosed
US-20190300688-A1 POLYPROPYLENE RESIN COMPOSITION AND MONOLAYER AND MULTILAYER FILM MITSUI CHEMICALS, INC. (JP) 2019-10-03 US disclosed
EP-3489298-A1 POLYPROPYLENE RESIN COMPOSITION AND SINGLE LAYER AND MULTILAYER FILM Mitsui Chemicals, Inc. (JP) 2019-05-29 EP disclosed
EP-2275457-B1 Propylene-based polymer composition, and molded products, sheets, films, laminates and non-woven fabrics obtained therefrom MITSUI CHEMICALS INC (JP) 2016-11-23 EP disclosed
EP-2080784-B1 PROPYLENE RESIN COMPOSITION, METHOD FOR PRODUCING PROPYLENE RESIN COMPOSITION, PROPYLENE POLYMER COMPOSITION, MOLDED BODY MADE OF THE PROPYLENE RESIN COMPOSITION, AND ELECTRIC WIRE MITSUI CHEMICALS INC (JP) 2013-03-06 EP disclosed
EP-2085420-A1 POLYPROPYLENE RESIN FILM AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2009-08-05 EP disclosed
EP-2080784-A1 PROPYLENE RESIN COMPOSITION, METHOD FOR PRODUCING PROPYLENE RESIN COMPOSITION, PROPYLENE POLYMER COMPOSITION, MOLDED BODY MADE OF THE PROPYLENE RESIN COMPOSITION, AND ELECTRIC WIRE Mitsui Chemicals, Inc. (JP) 2009-07-22 EP disclosed
EP-1900758-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE COPOLYMER, PROPYLENE POLYMER, PROPYLENE POLYMER COMPOSITION, AND USE OF THOSE Mitsui Chemicals, Inc. (JP) 2008-03-19 EP disclosed