SCHEMBL4429943

SCHEMBL4429943

CC(C)(C)c1cc2c(cc1C(C)(C)C)C([Zr](C1=CC=CC1)=C(c1ccccc1)c1cccc(C(F)(F)F)c1)c1cc(C(C)(C)C)c(C(C)(C)C)cc1-2

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.34
RBP4 P02753 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
TAS1R2 Q8TE23 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 4/20 0.32
MEN1 O00255 2/20 0.31
OPRM1 P35372 1/20 0.31
OPRL1 P41146 1/20 0.31
VNN1 O95497 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAOB P27338 1/20 0.31
KCNK3 O14649 1/20 0.31
SRD5A2 P31213 1/20 0.31
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14735793 0.97 CES2 (0.36) CES2RBP4TAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL811766 0.96 CES2 (0.36) CES2RBP4TAS1R3TAS1R1TAS1R2
SCHEMBL4434256 0.94 GAA (0.32) CES2RBP4TAS1R3TAS1R1TAS1R2
SCHEMBL4434269 0.94 ALDH1A1 (0.35) CES2RBP4TAS1R3TAS1R1TAS1R2
SCHEMBL14735586 0.93 ALDH1A1 (0.35) CES2RBP4TAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL812839 0.92 ALDH1A1 (0.35) CES2RBP4TAS1R3TAS1R1TAS1R2
SCHEMBL14735582 0.91 CES2 (0.34) CES2RBP4TAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL811910 0.90 CES2 (0.33) CES2RBP4TAS1R3TAS1R1TAS1R2
SCHEMBL4427085 0.90 ACHE (0.34) CES2RBP4TAS1R3TAS1R1TAS1R2
SCHEMBL4433941 0.89 ACHE (0.34) CES2TAS1R3TAS1R1TAS1R2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11492471-B2 Polypropylene resin composition and monolayer and multilayer film MITSUI CHEMICALS, INC. (JP) 2022-11-08 US disclosed
US-20190300688-A1 POLYPROPYLENE RESIN COMPOSITION AND MONOLAYER AND MULTILAYER FILM MITSUI CHEMICALS, INC. (JP) 2019-10-03 US disclosed
EP-2275457-B1 Propylene-based polymer composition, and molded products, sheets, films, laminates and non-woven fabrics obtained therefrom MITSUI CHEMICALS INC (JP) 2016-11-23 EP disclosed
EP-2080784-B1 PROPYLENE RESIN COMPOSITION, METHOD FOR PRODUCING PROPYLENE RESIN COMPOSITION, PROPYLENE POLYMER COMPOSITION, MOLDED BODY MADE OF THE PROPYLENE RESIN COMPOSITION, AND ELECTRIC WIRE MITSUI CHEMICALS INC (JP) 2013-03-06 EP disclosed
EP-2080784-A1 PROPYLENE RESIN COMPOSITION, METHOD FOR PRODUCING PROPYLENE RESIN COMPOSITION, PROPYLENE POLYMER COMPOSITION, MOLDED BODY MADE OF THE PROPYLENE RESIN COMPOSITION, AND ELECTRIC WIRE Mitsui Chemicals, Inc. (JP) 2009-07-22 EP disclosed
EP-1900758-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE COPOLYMER, PROPYLENE POLYMER, PROPYLENE POLYMER COMPOSITION, AND USE OF THOSE Mitsui Chemicals, Inc. (JP) 2008-03-19 EP disclosed