Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366924 | 0.86 | PARP1 (0.40) | PARP1ROCK2PIM1PIM3PARP15 | |
| SCHEMBL29120355 | 0.84 | PARP1 (0.39) | PARP1ROCK2PIM1PIM3PARP15 | |
| SCHEMBL4434522 | 0.81 | PARP1 (0.52) | PARP1GAAPARP15PARP10TSHR | |
| Terephthalamide SCHEMBL11492620 | 0.79 | PARP1 (0.47) | PARP1ROCK2PIM1PIM3TTK | |
| SCHEMBL8855118 | 0.75 | DHODH (0.45) | PARP1TSHRMEN1MAPTKMT2A | |
| SCHEMBL10707481 | 0.74 | LMNA (0.57) | PARP1MEN1MAPTKMT2AELANE | |
| Terephthalamide SCHEMBL11494225 | 0.72 | MAPT (0.58) | PARP1PARP15PARP10TSHRMEN1 | |
| SCHEMBL31021028 | 0.71 | PARP1 (0.73) | PARP1PARP15PARP10TSHRMEN1 | |
| SCHEMBL36694 | 0.71 | PARP1 (0.73) | PARP1PARP15PARP10TSHRMEN1 | |
| Water SCHEMBL7768285 | 0.69 | PARP1 (0.70) | PARP1PARP15PARP10TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502953-B1 | QUATERNARY AMMONIUM POLYARYLAMIDES | DU PONT (US) | 1996-02-07 | — | — | EP | claimed |
| US-5242991-A | Electronic circuits and molding materials | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-07 | — | — | US | claimed |
| EP-0502953-A1 | QUATERNARY AMMONIUM POLYARYLAMIDES. | DU PONT (US) | 1992-09-16 | — | — | EP | claimed |
| WO-1991008248-A1 | QUATERNARY AMMONIUM POLYARYLAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-13 | — | — | WO | claimed |
| US-5407626-A | Deprotenation of the amide N by reacting with a quaternary amine to form an anionic polymer; casting from solution; desolventizing; heating to alkylate or neutralize | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-04-18 | — | — | US | disclosed |
| US-5242991-A | Electronic circuits and molding materials | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-07 | — | — | US | disclosed |