Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089890 | 0.76 | PRCP (0.33) | — | |
| SCHEMBL11146381 | 0.75 | — | — | |
| SCHEMBL11279013 | 0.74 | DRD2 (0.34) | DRD2DRD3 | |
| SCHEMBL4434550 | 0.74 | — | — | |
| SCHEMBL2605419 | 0.74 | — | — | |
| SCHEMBL2852701 | 0.74 | — | — | |
| SCHEMBL15238182 | 0.74 | — | — | |
| SCHEMBL10498523 | 0.73 | DPP4 (0.32) | DPP4 | |
| SCHEMBL5580304 | 0.73 | HTR1A (0.44) | DRD2 | |
| SCHEMBL9685949 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060063932-A1 | Aminoalkylpyrrolidine serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their synthesis | RUI YUANJIN | 2006-03-23 | — | — | US | disclosed |
| EP-1339677-B1 | AMINOALKYLPYRROLIDINE SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SYNTHESIS | WARNER LAMBERT CO (US) | 2006-01-04 | — | — | EP | disclosed |
| US-20040039044-A1 | Aminoalkylpyrrolidine serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their synthesis | RUI YUANJIN (US) | 2004-02-26 | — | — | US | disclosed |
| EP-1339677-A1 | AMINOALKYLPYRROLIDINE SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SYNTHESIS | Warner-Lambert Company LLC (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002036560-A1 | AMINOALKYLPYRROLIDINE SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SYNTHESIS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-10 | — | — | WO | disclosed |
| EP-0000106-B1 | 2-ALKYL NICOTINOIDS AND PROCESSES FOR THEIR PRODUCTION AND USE | PHILIP MORRIS INCORPORATED (US) | 1982-02-17 | — | — | EP | disclosed |
| US-4220781-A | QUARTINIZATION, REARRANGEMENT AND REDUCTION | PHILIP MORRIS, INC. (US) | 1980-09-02 | — | — | US | disclosed |
| US-4155909-A | INSECTICIDES | PHILIP MORRIS INCORPORATED (US) | 1979-05-22 | — | — | US | disclosed |
| EP-0000106-A1 | 2-Alkyl nicotinoids and processes for their production and use | PHILIP MORRIS INCORPORATED (US) | 1978-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063932-A1 | Aminoalkylpyrrolidine serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their synthesis | HTR7, HTR5A, HTR1A | DPP4 2044/4885PREP 861/4885DRD2 44/4885 |
| US-20040039044-A1 | Aminoalkylpyrrolidine serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their synthesis | HTR7, HTR5A, HTR1A | DPP4 1934/4885PREP 853/4885DRD2 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.