SCHEMBL4434556

SCHEMBL4434556

CC(C)[C@@H](C)CC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.77

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.77
▸ MEN1 O00255 2/20 0.77
▸ KMT2A Q03164 2/20 0.77
▸ USP2 O75604 1/20 0.77
▸ MAPT P10636 1/20 0.77
▸ ALOX15 P16050 1/20 0.77
▸ DHCR24 Q15392 11/20 0.77
▸ TRPV1 Q8NER1 1/20 0.63
▸ THRB P10828 1/20 0.49
▸ NR1H3 Q13133 2/20 0.45
▸ CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5823900 1.00 ALDH1A1 (0.77) ALDH1A1MEN1KMT2AUSP2MAPT
SCHEMBL6900565 1.00 ALDH1A1 (0.77) ALDH1A1MEN1KMT2AUSP2MAPT
SCHEMBL1237838 1.00 ALDH1A1 (0.77) ALDH1A1MEN1KMT2AUSP2MAPT
SCHEMBL22318602 1.00 ALDH1A1 (0.77) ALDH1A1MEN1KMT2AUSP2MAPT
SCHEMBL599029 1.00 ALDH1A1 (0.77) ALDH1A1MEN1KMT2AUSP2MAPT
SCHEMBL30897555 1.00 ALDH1A1 (0.77) ALDH1A1MEN1KMT2AUSP2MAPT
SCHEMBL28186368 0.94 MEN1 (0.85) ALDH1A1MEN1KMT2AUSP2MAPT
SCHEMBL14911153 0.89 ALDH1A1 (0.80) ALDH1A1MEN1KMT2AUSP2MAPT
SCHEMBL15346215 0.89 ALDH1A1 (0.73) ALDH1A1MEN1KMT2AUSP2MAPT
SCHEMBL4625070 0.89 ALDH1A1 (0.73) ALDH1A1MEN1KMT2AUSP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7863470-B2 Linear polyethylenimine-sterol conjugates for gene delivery UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2011-01-04 — — US claimed
US-20070154447-A1 Linear polyethylenimine-sterol conjugates for gene delivery FURGESON DARIN Y 2007-07-05 — — US claimed
US-7183263-B2 Linear polyethylenimine-sterol conjugates for gene delivery UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2007-02-27 — — US claimed
US-20040137050-A1 Linear polyethylenimine-sterol conjugates for gene delivery THE UNIVERSITY OF UTAH RESEARCH FOUNDATION 2004-07-15 — — US claimed
EP-4731009-A1 LINSEED OIL PRODUCTION SYSTEM, LINSEED OIL PRODUCTION PROCESS AND LINSEED OIL LIN DES PYRÉNÉES (FR) 2026-04-29 — — EP disclosed
WO-2024235681-A1 LINSEED OIL PRODUCTION SYSTEM, LINSEED OIL PRODUCTION PROCESS AND LINSEED OIL Lin des Pyrénées (FR) 2024-11-21 — — WO disclosed
US-11918770-B2 Implants for localized drug delivery and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-05 — — US disclosed
CN-114159480-B Composition with weight-losing effect and preparation method and application thereof 夏文华 2022-08-30 — — CN disclosed
US-20220184362-A1 Implants for Localized Drug Delivery and Methods of Use Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-06-16 — — US disclosed
US-11324935-B2 Implants for localized drug delivery and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-10 — — US disclosed
CN-114159480-A Composition with weight-losing effect and preparation method and application thereof 广州臻卓生物技术有限公司 2022-03-11 — — CN disclosed
EP-3833737-A1 GENETICALLY-MODIFIED BACTERIA AND USES THEREOF Cambrex Karlskoga AB (SE) 2021-06-16 — — EP disclosed
US-20080181928-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY MIV THERAPEUTICS, INC. (CA) 2008-07-31 — — US disclosed
WO-2008077247-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING CHOLESTEROL MIV THERAPEUTICS INC. (CA) 2008-07-03 — — WO disclosed
WO-2008077248-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY MIV THERAPEUTICS INC. (CA) 2008-07-03 — — WO disclosed
US-20070254859-A1 Compounds exhibiting efflux inhibitor activity and composition and uses thereof EASTMAN CHEMICAL COMPANY 2007-11-01 — — US disclosed
US-20070154447-A1 Linear polyethylenimine-sterol conjugates for gene delivery FURGESON DARIN Y 2007-07-05 — — US disclosed
CN-1993126-A Use of a steroid for enhancement of skin permeability NOVARTIS AG (CH) 2007-07-04 — — CN disclosed
US-7183263-B2 Linear polyethylenimine-sterol conjugates for gene delivery UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2007-02-27 — — US disclosed
US-20040137050-A1 Linear polyethylenimine-sterol conjugates for gene delivery THE UNIVERSITY OF UTAH RESEARCH FOUNDATION 2004-07-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254859-A1 Compounds exhibiting efflux inhibitor activity and composition and uses thereof ABCC4, NCOA4, NR4A3 ALDH1A1 2000/4885MEN1 4281/4885KMT2A 4362/4885
US-20080181928-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY LIPA, SGMS2, SGMS1 ALDH1A1 4605/4885MEN1 748/4885KMT2A 2165/4885
US-20040137050-A1 Linear polyethylenimine-sterol conjugates for gene delivery LDLR, CETP, CYP11A1 ALDH1A1 4598/4885MEN1 1487/4885KMT2A 2146/4885
US-20070154447-A1 Linear polyethylenimine-sterol conjugates for gene delivery LDLR, CETP, CYP11A1 ALDH1A1 4598/4885MEN1 1487/4885KMT2A 2146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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