Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | MC4R | P32245 | 2/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444405 | 1.00 | ALDH1A1 (0.70) | ALDH1A1USP2HPGDMC4RHTR2C | |
| SCHEMBL31469959 | 0.91 | ALDH1A1 (0.65) | ALDH1A1USP2HPGDMC4RHTR2C | |
| SCHEMBL27309933 | 0.91 | ALDH1A1 (0.65) | ALDH1A1USP2HPGDMC4RHTR2C | |
| SCHEMBL2450751 | 0.91 | ALDH1A1 (0.65) | ALDH1A1USP2HPGDMC4RHTR2C | |
| SCHEMBL1792830 | 0.86 | MC4R (0.75) | ALDH1A1USP2HPGDMC4RHTR2C | |
| SCHEMBL2450367 | 0.86 | HTR2C (0.56) | ALDH1A1USP2HPGDHTR2CSMN1; SMN2 | |
| SCHEMBL29542019 | 0.86 | HTR2C (0.53) | ALDH1A1USP2HPGDHTR2CAURKA | |
| SCHEMBL2450444 | 0.86 | MC4R (0.58) | ALDH1A1USP2HPGDMC4RALOX12 | |
| SCHEMBL14813679 | 0.86 | MC4R (0.58) | ALDH1A1USP2HPGDMC4RALOX12 | |
| SCHEMBL5508510 | 0.84 | ALDH1A1 (0.56) | ALDH1A1USP2HPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9783796-B2 | Amidase, gene for the same, vector, transformant, and method for production of optically active carboxylic acid amide and optically active carboxylic acid by using any one of those items | KANEKA CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| US-20150065717-A1 | NIPECOTIC ACID DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | TORAY INDUSTRIES, INC. (JP) | 2015-03-05 | — | — | US | disclosed |
| EP-2128258-B1 | NOVEL AMIDASE, GENE FOR THE SAME, VECTOR, TRANSFORMANT, AND METHOD FOR PRODUCTION OF OPTICALLY ACTIVE CARBOXYLIC ACID AMIDE AND OPTICALLY ACTIVE CARBOXYLIC ACID BY USING ANY ONE OF THOSE ITEMS | KANEKA CORP (JP) | 2013-09-11 | — | — | EP | disclosed |
| US-20130059348-A1 | NOVEL AMIDASE, GENE FOR THE SAME, VECTOR, TRANSFORMANT, AND METHOD FOR PRODUCTION OF OPTICALLY ACTIVE CARBOXYLIC ACID AMIDE AND OPTICALLY ACTIVE CARBOXYLIC ACID BY USING ANY ONE OF THOSE ITEMS | KANEKA CORPORATION (JP) | 2013-03-07 | — | — | US | disclosed |
| EP-2128258-A1 | NOVEL AMIDASE, GENE FOR THE SAME, VECTOR, TRANSFORMANT, AND METHOD FOR PRODUCTION OF OPTICALLY ACTIVE CARBOXYLIC ACID AMIDE AND OPTICALLY ACTIVE CARBOXYLIC ACID BY USING ANY ONE OF THOSE ITEMS | Kaneka Corporation (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065717-A1 | NIPECOTIC ACID DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | NCEH1, REN, NIPSNAP1 | ALDH1A1 2137/4885USP2 1996/4885HPGD 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.