Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16428799 | 0.84 | ADRA2A (0.42) | NISCHPDE3BPDE3AMTORADK | |
| SCHEMBL1425562 | 0.84 | NISCH (0.42) | NISCHPDE3BPDE3AMTORADK | |
| SCHEMBL1463267 | 0.83 | NISCH (0.61) | NISCHMAPK1PDE3BPDE3AMTOR | |
| SCHEMBL15029205 | 0.81 | MAPK1 (0.42) | MAPK1ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL5556380 | 0.80 | MAPK1 (0.46) | NISCHMAPK1ALDH1A1KDM4ERAB9A | |
| SCHEMBL24575957 | 0.79 | NISCH (0.42) | NISCHPDE3BPDE3AMTORADK | |
| SCHEMBL771236 | 0.79 | NISCH (0.64) | NISCHMAPK1PDE3BPDE3AMTOR | |
| Hydrochloric Acid SCHEMBL28346045 | 0.77 | NISCH (0.62) | NISCHMAPK1PDE3BPDE3AMTOR | |
| Bromide SCHEMBL28348957 | 0.77 | NISCH (0.62) | NISCHMAPK1PDE3BPDE3AMTOR | |
| SCHEMBL24575959 | 0.75 | MAPK1 (0.48) | NISCHMAPK1MTORADKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673663-B1 | LIGHT SENSITIVE COATING COMPOSITIONS FOR LITHOGRAPHIC ELEMENTS | IBF IND BRASILEIRA DE FILMES SA (BR) | 2011-03-23 | — | — | EP | claimed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | FAAH, FAAH2, ASAH1 | NISCH 334/4885MAPK1 3471/4885PDE3B 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.