Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.45 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
| ▸ | CHUK | O15111 | 2/20 | 0.35 |
| ▸ | GCKR | Q14397 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431799 | 0.76 | GPR119 (0.43) | GPR119IKBKBCHUKPTGS2PLAT | |
| SCHEMBL3485771 | 0.73 | GPR119 (0.64) | GPR119 | |
| SCHEMBL2781696 | 0.68 | GPR119 (0.43) | GPR119IKBKBCHUK | |
| SCHEMBL3623650 | 0.68 | GPR119 (0.68) | GPR119 | |
| SCHEMBL4553713 | 0.67 | GPR119 (0.32) | GPR119IKBKBCHUKPTGS2 | |
| SCHEMBL14138626 | 0.66 | GPR119 (0.62) | GPR119 | |
| SCHEMBL4554614 | 0.64 | GPR119 (0.53) | GPR119 | |
| SCHEMBL4574071 | 0.64 | GPR119 (0.39) | GPR119PTGS2 | |
| SCHEMBL3625467 | 0.63 | GPR119 (0.49) | GPR119 | |
| SCHEMBL10276715 | 0.63 | GPR119 (0.70) | GPR119PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121661-A1 | BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck & Co., Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008085316-A1 | BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 2008-07-17 | — | — | WO | disclosed |