Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | GCK | P35557 | 4/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27752387 | 0.80 | SLC6A2 (0.45) | ADRB1 | |
| SCHEMBL3844598 | 0.69 | PKM (0.37) | — | |
| SCHEMBL4573023 | 0.68 | CHRM2 (0.37) | — | |
| SCHEMBL1458915 | 0.68 | PKM (0.34) | — | |
| Bromide SCHEMBL4573068 | 0.67 | CHRM2 (0.36) | — | |
| Hydrochloric Acid SCHEMBL4572925 | 0.66 | HTR2C (0.36) | — | |
| Hydrochloric Acid SCHEMBL3602383 | 0.66 | SLC9A3 (0.38) | GPR119PTGS2 | |
| SCHEMBL29264392 | 0.65 | PARP1 (0.41) | GPR119 | |
| Hydrochloric Acid SCHEMBL3602379 | 0.65 | HTR2C (0.38) | PTGS2 | |
| SCHEMBL532144 | 0.65 | ALDH1A1 (0.69) | GPR119ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |