Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 7/20 | 0.44 |
| ▸ | MMP12 | P39900 | 7/20 | 0.44 |
| ▸ | MMP13 | P45452 | 7/20 | 0.44 |
| ▸ | MMP14 | P50281 | 7/20 | 0.44 |
| ▸ | MMP9 | P14780 | 6/20 | 0.44 |
| ▸ | MMP8 | P22894 | 6/20 | 0.44 |
| ▸ | MMP16 | P51512 | 6/20 | 0.44 |
| ▸ | MMP1 | P03956 | 5/20 | 0.44 |
| ▸ | MMP3 | P08254 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24784076 | 0.88 | CYP2D6 (0.48) | CYP2D6CA12MMP2MMP12MMP13 | |
| SCHEMBL710752 | 0.87 | CYP2D6 (0.62) | CYP2D6MMP2MMP12MMP13MMP14 | |
| SCHEMBL24018769 | 0.85 | CYP2D6 (0.46) | CYP2D6CA12MMP2MMP12MMP13 | |
| SCHEMBL332353 | 0.84 | CYP2D6 (0.50) | CYP2D6CA12MMP2MMP12MMP13 | |
| SCHEMBL3263174 | 0.84 | POLB (0.52) | CYP2D6CA12HSD11B1 | |
| SCHEMBL24498677 | 0.84 | HSD11B1 (0.47) | CYP2D6CA12MMP2MMP12MMP13 | |
| SCHEMBL22957774 | 0.82 | CYP2D6 (0.43) | CYP2D6CA12MMP2MMP12MMP13 | |
| Ammonia Solution, Strong SCHEMBL4058946 | 0.82 | CYP2D6 (0.49) | CYP2D6CA12MMP2MMP12MMP13 | |
| SCHEMBL1804258 | 0.82 | CA2 (0.50) | CYP2D6CA12 | |
| SCHEMBL20854268 | 0.82 | CYP2D6 (0.49) | CYP2D6CA12MMP2MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061754-A1 | BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008115999-A1 | BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-25 | — | — | WO | disclosed |
| US-20080234384-A1 | BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-25 | — | — | US | disclosed |
| US-7306894-B2 | Polymerizable composition, photopolymerizing method and process for producing lithographic printing plate using the polymerizable composition | FUJIFILM CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| EP-1589374-A2 | Polymerizable composition, photopolymerizing method and process for producing lithographic printing plate using the polymerizable composition | Fuji Photo Film Co., Ltd. (JP) | 2005-10-26 | — | — | EP | disclosed |
| US-20050202341-A1 | Polymerizable composition, photopolymerizing method and process for producing lithographic printing plate using the polymerizable composition | FUJI PHOTO FILM CO., LTD. | 2005-09-15 | — | — | US | disclosed |
| US-5288781-A | Blended with polyether, sulfonate and sulfone components; antistatic, clarity, heat resistance, mechanical properties | SKC LIMITED (KR) | 1994-02-22 | — | — | US | disclosed |
| US-4057418-A | Sulfonylmethylamino-substituted benzoic acids and herbicidal method therewith | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234384-A1 | BIARYL AND BIHETEROARYL COMPOUNDS USEFUL IN TREATING IRON DISORDERS | FECH, SLC10A1, SLC40A1 | CYP2D6 70/4885CA12 967/4885MMP2 3525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.