SCHEMBL9027632

SCHEMBL9027632

CC[SiH2]OCCOS(=O)(=O)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1032931 0.78 CA2 (0.47) CA2CA1
SCHEMBL17537471 0.77 CA2 (0.36) CA2CA1
SCHEMBL777006 0.74 CA2 (0.48) CA2CA1
SCHEMBL946205 0.74 CA2 (0.39) CA2CA1
SCHEMBL4435018 0.73
Ethane Dimethane Sulfonate SCHEMBL8875130 0.73 USP2 (0.50) CA2CA1
SCHEMBL28166512 0.73 CA2 (0.46) CA2CA1
SCHEMBL1759185 0.73 CA2 (0.41) CA2CA1
Ammonia Solution, Strong SCHEMBL20185539 0.73 CA2 (0.46) CA2CA1
SCHEMBL4949086 0.72 CA2 (0.43) CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722447-A1 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-07-24 EP disclosed
WO-1995010520-A1 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-04-20 WO disclosed