Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3186530 | 0.86 | GPR119 (0.49) | S1PR5HRH3AKR1C3ABHD6GPR119 | |
| SCHEMBL4437451 | 0.80 | HRH3 (0.53) | HRH3ACACBGPR119 | |
| SCHEMBL3178990 | 0.80 | GPR119 (0.55) | S1PR5GPR119 | |
| SCHEMBL3181898 | 0.80 | S1PR5 (0.46) | S1PR5HRH3AKR1C3ABHD6ACACB | |
| SCHEMBL4437051 | 0.79 | HRH3 (0.41) | S1PR5HRH3NPY1RGPR119 | |
| SCHEMBL3170712 | 0.77 | GPR119 (0.49) | GPR119 | |
| SCHEMBL4563873 | 0.73 | MOGAT2 (0.54) | — | |
| SCHEMBL2251879 | 0.71 | GPR119 (0.49) | GPR119 | |
| SCHEMBL4434575 | 0.70 | ESR1 (0.42) | HRH3ACACB | |
| SCHEMBL4444433 | 0.69 | ESR2 (0.43) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114890-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-11-11 | — | — | EP | claimed |
| WO-2008097428-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2008-08-14 | — | — | WO | claimed |