Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 2/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435258 | 0.94 | CTSA (0.41) | FPR1CTSAMMP3CASP1 | |
| SCHEMBL4436967 | 0.93 | CTSA (0.41) | FPR1CYP26A1CTSA | |
| SCHEMBL4431712 | 0.93 | CTSA (0.41) | FPR1CYP26A1CTSA | |
| SCHEMBL4429736 | 0.92 | CTSA (0.41) | FPR1CTSAKMT2AITGB1ITGA4 | |
| SCHEMBL4436965 | 0.92 | FPR1 (0.43) | FPR1CYP26A1CTSAGCGRCASP1 | |
| SCHEMBL4435402 | 0.91 | FPR1 (0.41) | FPR1CYP26A1CTSAITGB1ITGA4 | |
| SCHEMBL7047526 | 0.90 | CTSA (0.39) | FPR1CTSAMMP3PTPN1CASP1 | |
| SCHEMBL4435400 | 0.90 | CTSA (0.40) | FPR1CYP26A1CTSAMMP3 | |
| SCHEMBL4435399 | 0.90 | CTSA (0.40) | FPR1CYP26A1CTSAMMP3 | |
| SCHEMBL8506622 | 0.90 | CTSA (0.40) | FPR1CYP26A1CTSAMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213288-B1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1213288-A1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-06-12 | — | — | EP | disclosed |