Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 2/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435266 | 0.92 | FPR1 (0.40) | FPR1GCGRCASP1CASP3CASP7 | |
| SCHEMBL4435402 | 0.91 | FPR1 (0.41) | FPR1CASP1CASP3CASP7CASP8 | |
| SCHEMBL4431146 | 0.89 | POLB (0.39) | FPR1CTSAPOLB | |
| SCHEMBL8506622 | 0.88 | CTSA (0.40) | FPR1CTSACYP26A1UTS2R | |
| SCHEMBL4435400 | 0.88 | CTSA (0.40) | FPR1CTSACYP26A1UTS2R | |
| SCHEMBL4435399 | 0.88 | CTSA (0.40) | FPR1CTSACYP26A1UTS2R | |
| SCHEMBL4427187 | 0.88 | MMP2 (0.38) | FPR1CASP1CTSAPOLB | |
| SCHEMBL7429087 | 0.88 | MMP2 (0.38) | FPR1CASP1CTSAPOLB | |
| SCHEMBL4436912 | 0.88 | SMN1; SMN2 (0.40) | FPR1CASP1 | |
| SCHEMBL4430253 | 0.88 | FPR1 (0.38) | FPR1CASP1CASP3CASP7CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213288-B1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1213288-A1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-06-12 | — | — | EP | disclosed |