Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15181971 | 0.76 | MGLL (0.41) | MGLLCYP1A2CYP3A4KMT2A | |
| SCHEMBL3589776 | 0.75 | HPGD (0.40) | MGLLALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15181970 | 0.71 | MGLL (0.41) | MGLLCYP1A2CYP3A4KMT2A | |
| SCHEMBL3592078 | 0.69 | HSD11B1 (0.43) | ALDH1A1SMN1; SMN2CYP3A4CYP2C19HTT | |
| SCHEMBL3586744 | 0.69 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL15181975 | 0.68 | HSD11B1 (0.44) | ALDH1A1SMN1; SMN2KCNA5KMT2A | |
| SCHEMBL15182313 | 0.67 | CHRNA7 (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3582432 | 0.67 | CACNA1D (0.42) | SMN1; SMN2KMT2A | |
| SCHEMBL3601518 | 0.66 | HSD11B1 (0.43) | ALDH1A1SMN1; SMN2CYP3A4CYP2C19HTT | |
| SCHEMBL3594022 | 0.66 | CNR1 (0.46) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | claimed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | claimed |
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |