Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437663 | 0.88 | SCN9A (0.42) | LMNAMAPTHTTSCN9AKMT2A | |
| SCHEMBL4439090 | 0.88 | SCN9A (0.42) | LMNAMAPTHTTSCN9AKMT2A | |
| SCHEMBL4439837 | 0.88 | SCN9A (0.42) | LMNAMAPTHTTSCN9AKMT2A | |
| SCHEMBL4438948 | 0.88 | LMNA (0.38) | LMNAMAPTHTTSCN9AKMT2A | |
| SCHEMBL4440072 | 0.85 | LMNA (0.39) | LMNAMAPTHTTSCN9AKMT2A | |
| SCHEMBL4437635 | 0.82 | LMNA (0.35) | LMNAMAPTHTTSCN9AKMT2A | |
| SCHEMBL4439973 | 0.81 | PBRM1 (0.44) | LMNAMAPTHTTKMT2AMEN1 | |
| SCHEMBL4440992 | 0.81 | MAPT (0.38) | LMNAMAPTHTTSCN9AKMT2A | |
| SCHEMBL4447058 | 0.81 | MAPT (0.36) | LMNAMAPTHTTSCN9AKMT2A | |
| SCHEMBL4444360 | 0.81 | LMNA (0.40) | LMNAMAPTHTTSCN9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | claimed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | claimed |
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |