Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437663 | 0.93 | SCN9A (0.42) | PBRM1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL4439090 | 0.93 | SCN9A (0.42) | PBRM1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL4439837 | 0.93 | SCN9A (0.42) | PBRM1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL4439829 | 0.84 | ALDH1A1 (0.41) | HTTCYP3A4CYP2C9CYP2C19NPSR1 | |
| SCHEMBL4444087 | 0.82 | KMT2A (0.38) | PBRM1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL4436766 | 0.82 | KMT2A (0.38) | PBRM1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL8789320 | 0.81 | GRM2 (0.43) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4438948 | 0.81 | LMNA (0.38) | PBRM1MEN1KMT2AHTTHTR2C | |
| SCHEMBL4435472 | 0.81 | LMNA (0.38) | MEN1KMT2AHTTHTR2CSLC6A4 | |
| SCHEMBL4439891 | 0.81 | FNTA (0.38) | HTTCYP2C9KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |