SCHEMBL4435898

SCHEMBL4435898

COC(=O)c1ccccc1NC=C(C)Cc1ccc(C(C)(C)C)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.45
KDM4E B2RXH2 6/20 0.44
POLB P06746 1/20 0.44
ATM Q13315 1/20 0.44
GLA P06280 1/20 0.43
ALDH1A1 P00352 4/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPT P10636 3/20 0.42
ALOX15 P16050 1/20 0.42
GAA P10253 2/20 0.41
MAPK1 P28482 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
RAB9A P51151 1/20 0.41
LMNA P02545 2/20 0.41
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
ELANE P08246 1/20 0.40
PRTN3 P24158 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4435895 1.00 KMT2A (0.45) KMT2AKDM4EPOLBATMGLA
SCHEMBL31412797 1.00 KMT2A (0.45) KMT2AKDM4EPOLBATMGLA
SCHEMBL15428443 0.88 HCAR2 (0.50) KMT2AKDM4EPOLBALDH1A1HSD17B10
SCHEMBL15428444 0.88 HCAR2 (0.50) KMT2AKDM4EPOLBALDH1A1HSD17B10
SCHEMBL27083626 0.86 KMT2A (0.52) KMT2AKDM4EPOLBATMGLA
SCHEMBL16269041 0.79 ALDH1A1 (0.53) KMT2AKDM4EPOLBATMGLA
SCHEMBL16269043 0.79 ALDH1A1 (0.53) KMT2AKDM4EPOLBATMGLA
SCHEMBL16269403 0.78 KMT2A (0.61) KMT2AKDM4EPOLBALDH1A1MAPT
SCHEMBL16269402 0.78 KMT2A (0.61) KMT2AKDM4EPOLBALDH1A1MAPT
SCHEMBL16269400 0.78 KMT2A (0.61) KMT2AKDM4EPOLBALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116568786-A Synergistic perfuming composition 弗门尼舍有限公司 2023-08-08 CN claimed
US-20230093639-A1 PERFUME SYSTEM FOR PERFUMED CONSUMER PRODUCT FIRMENICH SA (CH) 2023-03-23 US claimed
WO-2006102777-A1 SKIN LIGHTENING METHODS, COMPOSITIONS AND PRODUCTS GIVAUDAN SA (CH) 2006-10-05 WO claimed
EP-4301834-B9 USE OF ENZYMES FOR IMPROVING FRAGRANCE DEPOSITION NOVOZYMES AS (DK) 2025-06-18 EP disclosed
EP-4301834-B1 USE OF ENZYMES FOR IMPROVING FRAGRANCE DEPOSITION NOVOZYMES AS (DK) 2025-04-09 EP disclosed
EP-4446001-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2024-10-16 EP disclosed
EP-3720936-B1 3,7-DIMETHYLOCT-6-EN-1-YL METHYL CARBONATE AS PERFUME INGREDIENT GIVAUDAN SA (CH) 2024-08-14 EP disclosed
US-20240173230-A1 FRAGRANCE COMPOSITION GIVAUDAN SA (CH) 2024-05-30 US disclosed
US-20240141259-A1 USE OF ENZYMES FOR IMPROVING FRAGRANCE DEPOSITION NOVOZYMES A/S (DK) 2024-05-02 US disclosed
US-20240050335-A1 A SYNERGISTIC PERFUMING COMPOSITION FIRMENICH & CIE (CH) 2024-02-15 US disclosed
EP-4319715-A1 FRAGRANCE COMPOSITION Givaudan SA (CH) 2024-02-14 EP disclosed
WO-2017097884-A1 SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY GIVAUDAN SA (CH) 2017-06-15 WO disclosed
US-20170073614-A1 Perfume Compositions GIVAUDAN SA (CH) 2017-03-16 US disclosed
WO-2017017152-A1 2,4,7-TRIMETHYLOCT-6-EN-1-OL AS FRAGANCE INGREDIENT GIVAUDAN SA (CH) 2017-02-02 WO disclosed
WO-2016097024-A1 PERFUME COMPOSITIONS GIVAUDAN SA (CH) 2016-06-23 WO disclosed
EP-3004157-A1 OLFACTORY RECEPTORS INVOLVED IN THE PERCEPTION OF SWEAT CARBOXYLIC ACIDS AND THE USE THEREOF ChemCom S.A. (BE) 2016-04-13 EP disclosed
WO-2014191047-A1 OLFACTORY RECEPTORS INVOLVED IN THE PERCEPTION OF SWEAT CARBOXYLIC ACIDS AND THE USE THEREOF CHEMCOM S.A. (BE) 2014-12-04 WO disclosed
EP-2136772-A2 PERFUME COMPOSITIONS Givaudan Nederland Services B.V. (NL) 2009-12-30 EP disclosed
WO-2008113495-A2 PERFUME COMPOSITIONS GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2008-09-25 WO disclosed
WO-2006102777-A1 SKIN LIGHTENING METHODS, COMPOSITIONS AND PRODUCTS GIVAUDAN SA (CH) 2006-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230093639-A1 PERFUME SYSTEM FOR PERFUMED CONSUMER PRODUCT PORCN, FAAH2, FASN KMT2A 2287/4885KDM4E 3235/4885POLB 240/4885
US-20240173230-A1 FRAGRANCE COMPOSITION FABP2, FABP5, FAAH2 KMT2A 1473/4885KDM4E 2086/4885POLB 766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.