Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087428 | 1.00 | POLB (0.76) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL8094050 | 1.00 | POLB (0.76) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL8094543 | 0.93 | POLB (0.68) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL267666 | 0.91 | ALDH1A1 (0.70) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL14263355 | 0.89 | POLB (0.63) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL1644518 | 0.89 | POLB (0.63) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL4687550 | 0.89 | LOXL2 (0.88) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL10915611 | 0.89 | POLB (0.63) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL9136851 | 0.89 | POLB (0.63) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL4686835 | 0.89 | POLB (0.63) | POLBLOXL2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3366 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991655-B1 | COMPOSITIONS AND METHODS FOR ALTERING SECOND MESSENGER SIGNALING | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2024-04-10 | — | — | EP | claimed |
| EP-3606906-B1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | BASF SE (DE) | 2023-12-27 | — | — | EP | claimed |
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | claimed |
| EP-3649135-B1 | SYNTHESIS OF HALICHONDRINS | HARVARD COLLEGE (US) | 2022-12-28 | — | — | EP | claimed |
| US-11512046-B2 | Heterogeneous catalysts for the direct carbonylation of nitro aromatic compounds to isocyanates | BASF SE | 2022-11-29 | — | — | US | claimed |
| US-11241435-B2 | Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis | THE GENERAL HOSPITAL CORPORATION (US) | 2022-02-08 | — | — | US | claimed |
| EP-3092220-B1 | VITAMIN C PRODRUGS AND USES THEREOF | UNIV FLORIDA (US) | 2021-01-20 | — | — | EP | claimed |
| US-20210002210-A1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | BASF SE (DE) | 2021-01-07 | — | — | US | claimed |
| US-10870651-B2 | Inhibitors of cyclin-dependent kinase 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-12-22 | — | — | US | claimed |
| EP-3171874-B1 | IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2020-11-18 | — | — | EP | claimed |
| EP-0157828-A4 | PROCESS FOR THE PREPARATION OF URETHANES. | CATALYTICA ASSOCIATES (US) | 1987-01-22 | — | — | EP | claimed |
| US-4629804-A | Process for preparation of urethanes | CATALYTICA ASSOCIATES (US) | 1986-12-16 | — | — | US | claimed |
| WO-1986005178-A1 | PROCESS FOR THE PREPARATION OF URETHANES | CATALYTICA ASSOCIATES (US) | 1986-09-12 | — | — | WO | claimed |
| WO-1986005179-A1 | CARBONYLATION PROCESS | CATALYTICA ASSOCIATES (US) | 1986-09-12 | — | — | WO | claimed |
| US-4603216-A | RUTHENIUM-PHOSPHINE CATALYST | CATALYTICA ASSOCIATES (US) | 1986-07-29 | — | — | US | claimed |
| US-4600793-A | Process for the preparation of urethanes | CATALYTICA ASSOCIATES (US) | 1986-07-15 | — | — | US | claimed |
| EP-0157828-A1 | PROCESS FOR THE PREPARATION OF URETHANES. | CATALYTICA ASSOCIATES (US) | 1985-10-16 | — | — | EP | claimed |
| WO-1985001285-A1 | PROCESS FOR THE PREPARATION OF URETHANES | CATALYTICA ASSOCIATES (US) | 1985-03-28 | — | — | WO | claimed |
| US-4178455-A | FROM AROMATIC NITRO COMPOUND, ALCOHOL AND CARBON MONOXIDE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1979-12-11 | — | — | US | claimed |
| US-4170708-A | FROM AN AROMATIC NITRO COMPOUND, AN ALCOHOL, AND CARBON MONOXIDE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1979-10-09 | — | — | US | claimed |