Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087428 | 1.00 | POLB (0.76) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL44366 | 1.00 | POLB (0.76) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL8094543 | 0.93 | POLB (0.68) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL267666 | 0.91 | ALDH1A1 (0.70) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL14263355 | 0.89 | POLB (0.63) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL1644518 | 0.89 | POLB (0.63) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL4687550 | 0.89 | LOXL2 (0.88) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL10915611 | 0.89 | POLB (0.63) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL9136851 | 0.89 | POLB (0.63) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL4686835 | 0.89 | POLB (0.63) | POLBLOXL2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |