⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2827132 | 0.79 | — | — | |
| SCHEMBL23265399 | 0.77 | — | — | |
| SCHEMBL17304513 | 0.75 | CTSD (0.42) | — | |
| SCHEMBL27383514 | 0.74 | CTSD (0.34) | — | |
| SCHEMBL12335996 | 0.73 | CTSD (0.46) | — | |
| SCHEMBL22203520 | 0.73 | CTSD (0.41) | — | |
| SCHEMBL929623 | 0.73 | HPGD (0.32) | — | |
| SCHEMBL22900019 | 0.73 | MCL1 (0.41) | — | |
| SCHEMBL9007188 | 0.73 | CTSD (0.41) | — | |
| SCHEMBL7094591 | 0.71 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688000-A1 | ANTIBODY DRUG CONJUGATES | CSTONE PHARMACEUTICALS (SUZHOU) CO., LTD. (CN) | 2026-02-11 | — | — | EP | claimed |
| WO-2024208354-A1 | ANTIBODY DRUG CONJUGATES | CSTONE PHARMACEUTICALS (SUZHOU) CO., LTD. (CN) | 2024-10-10 | — | — | WO | claimed |
| EP-2465541-B1 | Improved processes for making hydrazides | WYETH LLC (US) | 2018-07-18 | — | — | EP | claimed |
| US-9738602-B2 | Processes for making hydrazides | WYETH LLC (US) | 2017-08-22 | — | — | US | claimed |
| EP-2155258-B1 | IMPROVED PROCESSES FOR MAKING HYDRAZIDES | WYETH LLC (US) | 2017-08-16 | — | — | EP | claimed |
| EP-1507556-B1 | CALICHEAMICIN DERIVATIVE-CARRIER CONJUGATES | WYETH HOLDINGS LLC (US) | 2016-07-27 | — | — | EP | claimed |
| US-20160176809-A1 | PROCESSES FOR MAKING HYDRAZIDES | WYETH LLC (US) | 2016-06-23 | — | — | US | claimed |
| US-9351986-B2 | Calicheamicin derivative-carrier conjugates | WYETH HOLDINGS LLC (US) | 2016-05-31 | — | — | US | claimed |
| US-9227924-B2 | Processes for making hydrazides | WYETH LLC (US) | 2016-01-05 | — | — | US | claimed |
| EP-2371392-B1 | Calicheamicin derivative-carrier conjugates | WYETH HOLDINGS LLC (US) | 2015-07-08 | — | — | EP | claimed |
| EP-1796735-A4 | IMMUNOTHERAPY OF AUTOIMMUNE DISORDERS | WYETH CORP (US) | 2007-12-12 | — | — | EP | claimed |
| US-20070264257-A1 | Immunotherapy of autoimmune disorders | WYETH LLC | 2007-11-15 | — | — | US | claimed |
| EP-1796735-A2 | IMMUNOTHERAPY OF AUTOIMMUNE DISORDERS | Wyeth a Corporation of the State of Delaware (US) | 2007-06-20 | — | — | EP | claimed |
| WO-2006042240-A2 | IMMUNOTHERAPY OF AUTOIMMUNE DISORDERS | WYETH (US) | 2006-04-20 | — | — | WO | claimed |
| EP-1507556-A2 | CALICHEAMICIN DERIVATIVE-CARRIER CONJUGATES | Wyeth Holdings Corporation (US) | 2005-02-23 | — | — | EP | claimed |
| US-20040192900-A1 | incubating cytotoxic drug derivatives and proteinaceous carrier in non-nucleophilic, protein-compatible, buffered solution, then chromatically separating; higher loading and reduced low conjugate fraction | WYETH HOLDINGS CORPORATION | 2004-09-30 | — | — | US | claimed |
| US-20040082764-A1 | Complex of antibodic and antibiotic with carrier | WYETH HOLDINGS CORPORATION | 2004-04-29 | — | — | US | claimed |
| WO-2003092623-A2 | CALICHEAMICIN DERIVATIVE-CARRIER CONJUGATES | WYETH HOLDINGS CORPORATION (US) | 2003-11-13 | — | — | WO | claimed |
| US-5770701-A | Process for preparing targeted forms of methyltrithio antitumor agents | AMERICAN CYANAMID COMPANY (US) | 1998-06-23 | — | — | US | claimed |
| US-5770710-A | REACTING METHYLTRITHIO ANTIBIOTIC LL-E32288 DERIVATIVE WITH MERCAPTAN COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1998-06-23 | — | — | US | claimed |