SCHEMBL4436694

SCHEMBL4436694

CCCCCCc1sccc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.42
GPR35 Q9HC97 1/20 0.42
RIPK1 Q13546 1/20 0.41
ALDH1A1 P00352 5/20 0.40
KCNH2 Q12809 3/20 0.38
ESR1 P03372 2/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
KDM4E B2RXH2 2/20 0.38
LMNA P02545 2/20 0.38
TP53 P04637 2/20 0.38
CYP3A4 P08684 2/20 0.38
HIF1A Q16665 2/20 0.38
HSD17B10 Q99714 2/20 0.38
SHBG P04278 1/20 0.38
HSPD1 P10809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21142475 1.00 ALOX5 (0.42) ALOX5GPR35RIPK1ALDH1A1KCNH2
SCHEMBL19304398 1.00 ALOX5 (0.42) ALOX5GPR35RIPK1ALDH1A1KCNH2
SCHEMBL5960013 1.00 ALOX5 (0.42) ALOX5GPR35RIPK1ALDH1A1KCNH2
SCHEMBL25765347 0.98 ALOX5 (0.43) ALOX5GPR35RIPK1ALDH1A1KCNH2
SCHEMBL8815622 0.92 ALOX5 (0.44) ALOX5RIPK1ALDH1A1KDM4ELMNA
SCHEMBL30954534 0.90 ALOX5 (0.43) ALOX5RIPK1ALDH1A1KDM4ELMNA
SCHEMBL7451426 0.83
SCHEMBL14690810 0.80 LTB4R (0.49) ALOX5GPR35TP53CYP3A4TYR
SCHEMBL6260351 0.80 LTB4R (0.49) ALOX5GPR35TP53CYP3A4TYR
SCHEMBL15648187 0.80 LTB4R (0.49) ALOX5GPR35TP53CYP3A4TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3696200-B1 PHOTORESPONSIVE HIGH-MOLECULAR WEIGHT MATERIAL, ADHESIVE, TONER, AND IMAGE FORMING METHOD KONICA MINOLTA INC (JP) 2024-08-28 EP disclosed
US-12037531-B2 Photoresponsive high-molecular weight material, adhesive, toner, and image forming method Konica Minolta, Inc. (JP) 2024-07-16 US disclosed
CN-111727493-B Patterned paste PPG工业俄亥俄公司 2024-01-26 CN disclosed
US-11702398-B2 Photoresponsive low-molecular weight material, adhesive, toner, and image forming method Konica Minolta, Inc. (JP) 2023-07-18 US disclosed
WO-2021113809-A1 ARYLAMIDES AND METHODS OF USE THEREOF GENZYME CORPORATION (US) 2021-06-10 WO disclosed
US-20090163693-A1 Photoactive aromatic polymers and preparation methods thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2009-06-25 US disclosed
WO-2008004751-A1 AROMATIC POLYMERS HAVING OPTICAL ACTIVITY AND PREPARATION METHODS THEREOF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2008-01-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11702398-B2 Photoresponsive low-molecular weight material, adhesive, toner, and image forming method ICAM1, CDH1, ACTR5 ALOX5 954/4885GPR35 492/4885RIPK1 1639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.