Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3592021 | 0.82 | HDAC1 (0.42) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3592019 | 0.82 | HDAC1 (0.42) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4747985 | 0.77 | CA1 (0.61) | KMT2ACA1CA2CA9 | |
| SCHEMBL4438981 | 0.73 | ALDH1A1 (0.46) | MEN1KMT2AHTT | |
| SCHEMBL15181797 | 0.73 | HTT (0.39) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3590822 | 0.73 | MEN1 (0.46) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3590816 | 0.73 | MEN1 (0.46) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3585646 | 0.72 | HTT (0.37) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4437675 | 0.72 | HTT (0.37) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3586449 | 0.72 | HTT (0.37) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | claimed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | claimed |