Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.74 |
| ▸ | IAPP | P10997 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661840 | 0.82 | TRPV1 (0.60) | TRPV1PKMCYP1A2CYP2D6MAPK1 | |
| SCHEMBL6235501 | 0.79 | TRPV1 (0.56) | TRPV1PKMCYP1A2CYP2D6MAPK1 | |
| SCHEMBL10503849 | 0.78 | TRPV1 (0.56) | TRPV1PKMCYP1A2CYP2D6MAPK1 | |
| SCHEMBL1245168 | 0.76 | CYP1A2 (0.57) | TRPV1PKMCYP1A2CYP2D6MAPK1 | |
| SCHEMBL7193940 | 0.73 | TRPV1 (0.62) | TRPV1PKMCYP1A2CYP2D6MAPK1 | |
| SCHEMBL28228079 | 0.73 | CYP1A2 (0.54) | TRPV1PKMCYP1A2CYP2D6MAPK1 | |
| SCHEMBL12260115 | 0.71 | TRPV1 (0.49) | TRPV1PKMCYP1A2CYP2D6CYP3A4 | |
| Thymol SCHEMBL4436995 | 0.71 | TRPA1 (0.58) | TRPV1IAPPPKMCYP1A2CYP3A4 | |
| SCHEMBL10271616 | 0.71 | TRPV1 (0.48) | TRPV1PKMCYP1A2CYP2D6MAPK1 | |
| SCHEMBL69265 | 0.70 | CYP1A2 (0.58) | TRPV1PKMCYP1A2CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2043620-A2 | COMPOSITIONS AND METHODS FOR TREATING PARASITIC INFECTIONS | Tyratech, Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008003007-A2 | COMPOSITIONS AND METHODS FOR TREATING PARASITIC INFECTIONS | TYRATECH, INC. (US) | 2008-01-03 | — | — | WO | disclosed |