Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CPN1 | P15169 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16215819 | 0.84 | ALDH1A1 (0.41) | GNAI3GNAO1GNAI1CACNA1BALDH1A1 | |
| SCHEMBL21159869 | 0.80 | ALDH1A1 (0.41) | GNAI3GNAO1GNAI1ALDH1A1NPC1 | |
| SCHEMBL3968814 | 0.80 | GNAI3 (0.53) | GNAI3GNAO1GNAI1CACNA1BALDH1A1 | |
| SCHEMBL2439450 | 0.80 | GNAI3 (0.53) | GNAI3GNAO1GNAI1CACNA1BALDH1A1 | |
| Hydrochloric Acid SCHEMBL1062724 | 0.78 | GNAI3 (0.56) | GNAI3GNAO1GNAI1CACNA1BALDH1A1 | |
| SCHEMBL11717 | 0.78 | GNAI3 (0.61) | GNAI3GNAO1GNAI1CACNA1BALDH1A1 | |
| SCHEMBL13673699 | 0.78 | ALDH1A1 (0.64) | GNAI3GNAO1GNAI1CACNA1BALDH1A1 | |
| SCHEMBL3427864 | 0.78 | GNAI3 (0.51) | GNAI3GNAO1GNAI1CACNA1BALDH1A1 | |
| SCHEMBL25024038 | 0.78 | ALDH1A1 (0.39) | GNAI3GNAO1GNAI1ALDH1A1NPC1 | |
| SCHEMBL15337702 | 0.78 | ALDH1A1 (0.64) | ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132176-A1 | 4-PIPERIDINYLUREA COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | Arete Therapeutics, Inc. (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008112022-A1 | 4 -PI PERIDINYLUREA COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | ARETE THERAPEUTICS, INC. (US) | 2008-09-18 | — | — | WO | disclosed |