Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26159879 | 0.87 | DPP4 (0.44) | ALDH1A1NPC1CHRM2CHRM4CHRM1 | |
| SCHEMBL1713070 | 0.84 | ALDH1A1 (0.42) | ALDH1A1NPC1CHRM2CHRM4CHRM1 | |
| SCHEMBL16215819 | 0.82 | ALDH1A1 (0.41) | ALDH1A1NPC1DPP4DPP7MEN1 | |
| SCHEMBL4437201 | 0.80 | GNAI3 (0.51) | ALDH1A1NPC1CHRM2CHRM1CHRM3 | |
| SCHEMBL15337702 | 0.80 | ALDH1A1 (0.64) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25024038 | 0.80 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9AGNAI3GNAO1 | |
| SCHEMBL9275712 | 0.80 | ALDH1A1 (0.48) | ALDH1A1NPC1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1713072 | 0.79 | ALDH1A1 (0.42) | ALDH1A1NPC1CHRM2CHRM4CHRM1 | |
| SCHEMBL2906606 | 0.78 | L3MBTL1 (0.54) | ALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL4164572 | 0.77 | ALDH1A1 (0.41) | ALDH1A1NPC1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019135010-A1 | TIACUMICIN DERIVATIVES AND THEIR USE AS ANTIBIOTICS | Universität Zürich (CH) | 2019-07-11 | — | — | WO | disclosed |