Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.44 |
| ▸ | MOGAT2 | Q3SYC2 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184623 | 0.86 | GPR119 (0.53) | ESR1ESR2ACACB | |
| SCHEMBL4437451 | 0.83 | HRH3 (0.53) | ESR1ESR2ACACBHRH3MOGAT2 | |
| SCHEMBL4434244 | 0.76 | HRH3 (0.53) | ESR1ESR2ACACBHRH3MOGAT2 | |
| SCHEMBL3178592 | 0.75 | GPR119 (0.55) | ESR1ESR2ACACBHRH3 | |
| SCHEMBL3186712 | 0.75 | GPR119 (0.62) | ACACB | |
| SCHEMBL3184728 | 0.74 | GPR119 (0.54) | ACACB | |
| SCHEMBL14116821 | 0.72 | HRH3 (0.45) | ESR1ESR2ACACBHRH3MOGAT2 | |
| SCHEMBL3186563 | 0.72 | GPR119 (0.52) | ACACB | |
| SCHEMBL3188326 | 0.72 | HRH3 (0.55) | ESR2ACACBHRH3 | |
| SCHEMBL3181847 | 0.72 | GPR119 (0.56) | ACACBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114890-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-11-11 | — | — | EP | claimed |
| WO-2008097428-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2008-08-14 | — | — | WO | claimed |