Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440894 | 1.00 | PNMT (0.59) | PNMTCES2BCHENPC1RAB9A | |
| SCHEMBL20764994 | 0.86 | PNMT (0.56) | PNMTCES2BCHETACR1ACP3 | |
| SCHEMBL382192 | 0.84 | PNMT (0.50) | PNMTCES2BCHETACR1ACP3 | |
| SCHEMBL4447858 | 0.84 | PNMT (0.51) | PNMTCES2NPC1RAB9AMEN1 | |
| SCHEMBL3447393 | 0.83 | SLC6A9 (0.46) | PNMTCES2BCHETACR1ACP3 | |
| SCHEMBL3447470 | 0.83 | MEN1 (0.47) | PNMTCES2BCHERAB9ATACR1 | |
| Hydrochloric Acid SCHEMBL381834 | 0.83 | PNMT (0.49) | PNMTCES2BCHETACR1ACP3 | |
| SCHEMBL27673058 | 0.81 | NPC1 (0.50) | CES2NPC1RAB9ATACR1ACP3 | |
| SCHEMBL257275 | 0.81 | PNMT (0.51) | PNMTCES2BCHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL167658 | 0.81 | PNMT (0.54) | PNMTCES2BCHERAB9ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672953-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL INHIBITORS | Acesion Pharma ApS (DK) | 2020-07-01 | — | — | EP | disclosed |
| WO-2019038315-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL INHIBITORS | ACESION PHARMA APS (DK) | 2019-02-28 | — | — | WO | disclosed |
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |