Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR1F | P30939 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1165573 | 0.85 | KDM4E (0.68) | KDM4ELMNAPKMHSD17B10ALDH1A1 | |
| SCHEMBL31487317 | 0.85 | KDM4E (0.68) | KDM4ELMNAPKMHSD17B10ALDH1A1 | |
| SCHEMBL27191679 | 0.85 | EGFR (0.68) | KDM4ELMNAHSD17B10ALDH1A1HPGD | |
| SCHEMBL5198795 | 0.84 | KDM4E (0.64) | KDM4ELMNAPKMHSD17B10ALDH1A1 | |
| SCHEMBL9536890 | 0.83 | LMNA (0.62) | KDM4ELMNAPKMHSD17B10ALDH1A1 | |
| SCHEMBL3107169 | 0.82 | KDM4E (0.61) | KDM4ELMNAPKMHSD17B10ALDH1A1 | |
| SCHEMBL4266152 | 0.82 | HTR6 (0.70) | KDM4ELMNAPKMHSD17B10ALDH1A1 | |
| SCHEMBL17674200 | 0.81 | KDM4E (0.45) | KDM4ELMNAALDH1A1HPGDMAPT | |
| SCHEMBL11626470 | 0.81 | KDM4E (0.60) | KDM4ELMNAPKMHSD17B10ALDH1A1 | |
| SCHEMBL19193162 | 0.81 | KDM4E (0.60) | KDM4ELMNAPKMHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2943493-B1 | THERAPEUTIC COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | GILEAD SCIENCES INC (US) | 2017-08-02 | — | — | EP | disclosed |
| WO-2014110296-A1 | THERAPEUTIC COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2014-07-17 | — | — | WO | disclosed |
| EP-2134683-A2 | NOVEL INHIBITORS HEPATITIS C VIRUS REPLICATION | Intermune, Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008100867-A2 | NOVEL INHIBITORS HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2008-08-21 | — | — | WO | disclosed |