Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4438564 | 0.90 | PKM (0.46) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4556269 | 0.86 | PLAU (0.47) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4438562 | 0.82 | KMT2A (0.45) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2814444 | 0.82 | KMT2A (0.62) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4556079 | 0.79 | AAK1 (0.53) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4556042 | 0.78 | ESR1 (0.49) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4446507 | 0.77 | PKM (0.53) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4448111 | 0.76 | LMNA (0.48) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4556271 | 0.76 | PKM (0.46) | PKMKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4555806 | 0.76 | MEN1 (0.51) | PKMKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | claimed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | claimed |