Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448117 | 0.90 | LMNA (0.46) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL4556335 | 0.88 | NPC1 (0.58) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4448114 | 0.83 | LMNA (0.48) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL4555050 | 0.82 | MAPT (0.45) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL2814444 | 0.80 | KMT2A (0.62) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL2624651 | 0.80 | HPSE (0.64) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL4556337 | 0.78 | NPC1 (0.56) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4555539 | 0.77 | MAPT (0.50) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL4556269 | 0.76 | PLAU (0.47) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL4438559 | 0.76 | PKM (0.47) | LMNAMAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | claimed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | claimed |