Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA6 | P23280 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27317514 | 0.84 | RELA (0.55) | RELALMNACYP2C19BLMSLC6A6 | |
| SCHEMBL6244763 | 0.82 | RELA (0.49) | RELACYP2C19CYP3A4CA12CA7 | |
| SCHEMBL27015945 | 0.82 | RELA (0.37) | RELALMNACYP2C19BLMSLC6A6 | |
| SCHEMBL7101625 | 0.82 | LMNA (0.40) | RELALMNACYP2C19BLMSLC6A6 | |
| SCHEMBL1408713 | 0.82 | CYP2C19 (0.40) | RELALMNACYP2C19BLMSLC6A6 | |
| SCHEMBL29631557 | 0.80 | LMNA (0.56) | RELALMNACYP2C19BLMSLC6A6 | |
| SCHEMBL26552089 | 0.80 | RELA (0.40) | RELALMNACYP2C19BLMSLC6A6 | |
| SCHEMBL6044984 | 0.79 | RELA (0.59) | RELALMNACA12CA7CA14 | |
| SCHEMBL6044977 | 0.79 | RELA (0.59) | RELACA12CA7CA14ALDH1A1 | |
| SCHEMBL19283671 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065112-A1 | LUBRICANT COMPOSITION WITH IMPROVED VARNISH DEPOSIT RESISTANCE | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2012-03-15 | — | — | US | disclosed |