Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 4/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443901 | 0.82 | RELA (0.40) | LMNASLC6A6CYP2C19BLMRELA | |
| SCHEMBL29631557 | 0.79 | LMNA (0.56) | LMNASLC6A6CYP2C19BLMRELA | |
| SCHEMBL27317514 | 0.78 | RELA (0.55) | LMNASLC6A6CYP2C19BLMRELA | |
| SCHEMBL3668580 | 0.76 | CA1 (0.39) | RELAALDH1A1HPGD | |
| SCHEMBL1408713 | 0.76 | CYP2C19 (0.40) | LMNASLC6A6CYP2C19BLMRELA | |
| SCHEMBL26552089 | 0.74 | RELA (0.40) | LMNASLC6A6CYP2C19BLMRELA | |
| SCHEMBL3665147 | 0.73 | RELA (0.46) | LMNARELAALDH1A1HPGD | |
| SCHEMBL6044977 | 0.73 | RELA (0.59) | RELAALDH1A1HPGD | |
| SCHEMBL1050009 | 0.72 | — | — | |
| SCHEMBL671558 | 0.71 | LMNA (0.39) | LMNASLC6A6CYP2C19BLMRELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988551-B1 | CHEMILUMINESCENT ENERGY TRANSFER CONJUGATES AND THEIR USES AS LABELS IN BINDING ASSAYS | BAYER AG (US) | 2003-09-10 | — | — | EP | disclosed |
| US-6165800-A | Chemiluminescent energy transfer conjugates and their uses as labels in binding assays | BAYER CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0988551-A2 | CHEMILUMINESCENT ENERGY TRANSFER CONJUGATES AND THEIR USES AS LABELS IN BINDING ASSAYS | Bayer Corporation (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998054574-A2 | CHEMILUMINESCENT ENERGY TRANSFER CONJUGATES AND THEIR USES AS LABELS IN BINDING ASSAYS | BAYER CORPORATION (US) | 1998-12-03 | — | — | WO | disclosed |