Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 9/20 | 0.39 |
| ▸ | IL2 | P60568 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437593 | 0.84 | NOTUM (0.43) | PDE2ANOTUMPDE10A | |
| SCHEMBL4438085 | 0.82 | NOTUM (0.33) | NOTUM | |
| SCHEMBL4426244 | 0.79 | PTGDR2 (0.41) | — | |
| SCHEMBL4431126 | 0.79 | ALKBH3 (0.37) | — | |
| SCHEMBL4608932 | 0.79 | HTR2B (0.36) | PDE2AHSD11B1PDE10A | |
| SCHEMBL147631 | 0.77 | KIF11 (0.45) | CYP1A2 | |
| SCHEMBL4428497 | 0.76 | HTT (0.35) | — | |
| SCHEMBL4429675 | 0.76 | PDE2A (0.39) | PDE2AHSD11B1CTSSCTSKKDM1A | |
| SCHEMBL693639 | 0.75 | NOTUM (0.45) | CTSSCTSKCYP1A2NOTUM | |
| SCHEMBL143472 | 0.74 | IKBKB (0.43) | KDM1ACYP1A2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121660-A2 | FUNGICIDAL AMIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008091580-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |