Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 8/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439285 | 0.86 | PDE2A (0.39) | PDE2AMCL1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4439151 | 0.84 | NOTUM (0.43) | PDE2AMCL1KIF11CYP1A2 | |
| SCHEMBL4429962 | 0.82 | ALKBH3 (0.36) | ALDH1A1LMNAL3MBTL1CYP1A2 | |
| SCHEMBL4429907 | 0.82 | KIF11 (0.36) | KIF11 | |
| SCHEMBL4432021 | 0.79 | CETP (0.39) | PDE2AALDH1A1L3MBTL1KIF11 | |
| SCHEMBL4607250 | 0.79 | S1PR4 (0.36) | PDE2AALDH1A1 | |
| SCHEMBL4431199 | 0.77 | NOTUM (0.43) | PDE2AMCL1HSD11B1 | |
| SCHEMBL4427280 | 0.76 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1 | |
| SCHEMBL4439265 | 0.76 | PDE2A (0.39) | PDE2AMCL1HSD11B1CTSSCTSK | |
| SCHEMBL4439316 | 0.76 | ALKBH3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121660-A2 | FUNGICIDAL AMIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008091580-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |