Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439603 | 0.82 | TSHR (0.46) | TSHRSMN1; SMN2KMT2ALMNAPOLB | |
| SCHEMBL4448939 | 0.81 | TSHR (0.45) | TSHRSMN1; SMN2KMT2ALMNAPOLB | |
| SCHEMBL4623701 | 0.80 | TSHR (0.62) | TSHRSMN1; SMN2KMT2ALMNAPOLB | |
| SCHEMBL4445360 | 0.80 | TSHR (0.43) | TSHRSMN1; SMN2KMT2ALMNAPOLB | |
| SCHEMBL4623561 | 0.79 | TSHR (0.60) | TSHRSMN1; SMN2KMT2ALMNAPOLB | |
| SCHEMBL4623474 | 0.78 | TSHR (0.56) | TSHRSMN1; SMN2KMT2ALMNAPOLB | |
| SCHEMBL17845833 | 0.78 | TSHR (0.42) | TSHRSMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL482900 | 0.76 | TSHR (0.40) | TSHRSMN1; SMN2KMT2ALMNANPC1 | |
| SCHEMBL1751580 | 0.76 | TSHR (0.73) | TSHRSMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL4624413 | 0.76 | TSHR (0.55) | TSHRSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129225-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. Du Pont de Nemours and Company (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008124092-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-16 | — | — | WO | disclosed |