Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12466762 | 0.93 | PPARG (0.38) | KMT2AMEN1MAOBPPARGHSP90AA1 | |
| SCHEMBL482900 | 0.83 | TSHR (0.40) | TSHRKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL9958047 | 0.83 | IDO1 (0.39) | KMT2AMEN1SMN1; SMN2MAOBHSP90AA1 | |
| SCHEMBL166893 | 0.82 | KDM4E (0.41) | KMT2AMEN1MAOBHSP90AA1IDO1 | |
| SCHEMBL4439603 | 0.80 | TSHR (0.46) | TSHRKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL4448939 | 0.79 | TSHR (0.45) | TSHRKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL3236733 | 0.79 | NPC1 (0.49) | TSHRKMT2AMEN1MAOBPPARG | |
| SCHEMBL18243 | 0.79 | NPC1 (0.49) | TSHRKMT2AMEN1MAOBPPARG | |
| SCHEMBL4439591 | 0.78 | TSHR (0.54) | TSHRKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL4445360 | 0.78 | TSHR (0.43) | TSHRKMT2AMEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016099916-A1 | POLYLACTIC ACID COMPOSITIONS WITH ACCELERATED DEGRADATION RATE AND INCREASED HEAT STABILITY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-06-23 | — | — | WO | disclosed |