Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | REN | P00797 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439603 | 0.90 | TSHR (0.46) | TSHRSMN1; SMN2KMT2ARENCYP3A4 | |
| SCHEMBL4448939 | 0.85 | TSHR (0.45) | TSHRSMN1; SMN2KMT2ARENCYP3A4 | |
| SCHEMBL4439591 | 0.80 | TSHR (0.54) | TSHRSMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL17845833 | 0.78 | TSHR (0.42) | TSHRSMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL482900 | 0.77 | TSHR (0.40) | TSHRSMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL3322588 | 0.77 | TSHR (0.40) | TSHRSMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL3322589 | 0.77 | TSHR (0.40) | TSHRSMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL4623701 | 0.71 | TSHR (0.62) | TSHRSMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL4623561 | 0.70 | TSHR (0.60) | TSHRSMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL12466762 | 0.70 | PPARG (0.38) | KMT2AMEN1MAPK1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129225-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. Du Pont de Nemours and Company (US) | 2009-12-09 | — | — | EP | claimed |
| WO-2008124092-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-16 | — | — | WO | claimed |