SCHEMBL443988

SCHEMBL443988

[CH]c1cccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6011843 0.67
Ethyne SCHEMBL864028 0.67 L3MBTL1 (0.52)
SCHEMBL42872 0.67
SCHEMBL27279903 0.65
SCHEMBL12683491 0.65 CES2 (0.62)
Hydrochloric Acid SCHEMBL28510091 0.65
SCHEMBL28912240 0.65 FBP1 (0.39)
SCHEMBL3545 0.65 L3MBTL1 (0.57)
SCHEMBL16291133 0.65 L3MBTL1 (0.57)
SCHEMBL24577735 0.63 DAO (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024083220-A1 LIGAND-OLIGONUCLEOTIDE CONJUGATE AND LINKER FOR CONJUGATE 上海京新生物医药有限公司 2024-04-25 WO claimed
CN-112707899-B Preparation method of quininol 东莞市东阳光动物保健药品有限公司 2023-10-17 CN claimed
CN-116102573-A Thienopyrimidine compound containing thiophene methylene structure and preparation method and application thereof 山东省药学科学院 2023-05-12 CN claimed
CN-114805346-A Heterocyclic derivative, preparation method and application thereof 成都硕德药业有限公司 2022-07-29 CN claimed
EP-4005384-A1 HERBICIDAL COMPOSITION CONTAINING R-TYPE PYRIDYLOXY CARBOXYLIC ACID DERIVATIVE AND USE THEREOF Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) 2022-06-01 EP claimed
CN-114560855-A Cycloalkylcarboxamide derivative, preparation method and application thereof 成都苑东生物制药股份有限公司 2022-05-31 CN claimed
CN-113735875-A Preparation method of guaiane sesquiterpene dimer 中国科学院昆明植物研究所 2021-12-03 CN claimed
CN-113666922-A Internal sulfonamide compounds and methods of use thereof 正大天晴药业集团股份有限公司 2021-11-19 CN claimed
CN-113661995-A Herbicidal composition comprising R-type pyridyloxycarboxylic acid derivative and synthetic hormone inhibitor and application thereof 青岛清原化合物有限公司 2021-11-19 CN claimed
EP-3904341-A1 R-TYPE PYRIDYLOXYCARBOXYLIC ACID, SALT AND ESTER DERIVATIVE THEREOF, AND PREPARATION METHOD THEREFOR, AND HERBICIDAL COMPOSITION AND APPLICATION THEREOF Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) 2021-11-03 EP claimed
US-5607928-A Carbapenem derivatives containing a bicyclic ketone substituent and their use as anti-infectives ZENECA LIMITED (GB) 1997-03-04 US claimed
EP-0595995-B1 ARYLAMIDOALKYL- AND ARYLAMINOALKYL-N-HYDROXYUREA COMPOUNDS AND -N-HYDROXYFORMAMIDE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY ABBOTT LAB (US) 1997-01-15 EP claimed
EP-0695753-A1 Carbapenem derivatives containing a bicyclic substituent, process for their preparation, and their use ZENECA LIMITED (GB) 1996-02-07 EP claimed
EP-0636136-A1 2-AMINOSUGAR DERIVATIVES OF MACROLIDES. PFIZER (US) 1995-02-01 EP claimed
EP-0595995-A4 ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY ABBOTT LAB (US) 1994-08-24 EP claimed
EP-0595995-A1 ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY. ABBOTT LAB (US) 1994-05-11 EP claimed
US-5258380-A Antiallergens, antihistamines JANSSEN PHARMACEUTICA N.V. (BE) 1993-11-02 US claimed
WO-1993018048-A1 2-AMINOSUGAR DERIVATIVES OF MACROLIDES PFIZER, INC. (US) 1993-09-16 WO claimed
WO-1993002037-A1 ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY ABBOTT LABORATORIES (US) 1993-02-04 WO claimed
US-4500467-A ANGIOTENSIN INHIBITORS, HYPOTENSIVE AGENTS BASF AKTIENGESELLSCAFT (DE) 1985-02-19 US claimed