SCHEMBL4440398

SCHEMBL4440398

O=C(OC(=O)c1ccc([N+](=O)[O-])c2ccccc12)c1ccc([N+](=O)[O-])c2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSB P07858 5/20 0.56
TDP1 Q9NUW8 2/20 0.52
ALDH1A1 P00352 6/20 0.46
AKR1C4 P17516 2/20 0.45
AKR1C3 P42330 2/20 0.45
AKR1C2 P52895 2/20 0.45
AKR1C1 Q04828 2/20 0.45
AR P10275 2/20 0.44
JMJD7 P0C870 1/20 0.41
CASP6 P55212 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
BRD4 O60885 1/20 0.41
LMNA P02545 1/20 0.41
HSP90AA1 P07900 1/20 0.41
MAPT P10636 1/20 0.41
CHRM1 P11229 1/20 0.41
DRD2 P14416 1/20 0.41
ALOX12 P18054 1/20 0.41
ADRA2B P18089 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4958070 0.90 TDP1 (0.62) CTSBTDP1ALDH1A1AKR1C4AKR1C3
SCHEMBL5789105 0.87 AKR1C4 (0.55) CTSBTDP1ALDH1A1AKR1C4AKR1C3
SCHEMBL1505185 0.86 ALDH1A1 (0.60) CTSBTDP1ALDH1A1CASP6MAPT
SCHEMBL29475630 0.82 CTSB (0.59) CTSBTDP1ALDH1A1AKR1C4AKR1C3
SCHEMBL9694148 0.82 CTSB (0.59) CTSBTDP1ALDH1A1AKR1C4AKR1C3
SCHEMBL2778988 0.82 CTSB (0.59) CTSBTDP1ALDH1A1AKR1C4AKR1C3
SCHEMBL13110624 0.81 CTSB (0.58) CTSBTDP1ALDH1A1AKR1C4AKR1C3
SCHEMBL26656853 0.81 CTSB (0.58) CTSBTDP1ALDH1A1AKR1C4AKR1C3
SCHEMBL6815898 0.81 CTSB (0.58) CTSBTDP1ALDH1A1AKR1C4AKR1C3
SCHEMBL7788656 0.79 TDP1 (0.80) CTSBTDP1ALDH1A1ARCASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250044298-A1 Oligosaccharide-Fluorescent Marker, and Preparation Method and Use thereof UNIV JIANGNAN (CN) 2025-02-06 US disclosed
CN-115504934-A Naphthalimide-nitrone compound and preparation method and application thereof 中国医学科学院药物研究所 2022-12-23 CN disclosed
WO-2022077052-A1 PROBE COMPOUNDS FOR MITOCHONDIAL MEMBRANE IMAGING THE UNIVERSITY OF SYDNEY (AU) 2022-04-21 WO disclosed
WO-2015013456-A1 INDICATOR COMPOUNDS, POLYMERIZABLE DERIVATIVES THEREOF AND INFECTION INDICATING MEDICAL DEVICES COMPRISING THE SAME INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2015-01-29 WO disclosed
EP-1871844-B1 BUBBLE COMPOSITION WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2014-08-27 EP disclosed
EP-2118065-B1 Substituted 1H-benz[de]isoquinoline-1,3-diones COUNCIL SCIENT IND RES (IN) 2013-08-14 EP disclosed
US-8211613-B2 prints, color filters, electronics, layer insulation films, wire covering films, optics, circuits, antireflection films, holograms and construction materials comprising a cured mixture of photosensitive resins and photoiniitiators having a naphthalimide structure DAI NIPPON PRINTING CO., LTD. (JP) 2012-07-03 US disclosed
EP-2118065-A1 NOVEL SUBSTITUTED 1H-BENZ ÝDE¨ISOQUINOLINE-1, 3 -DIONES Council of Scientific & Industrial Research (IN) 2009-11-18 EP disclosed
US-20080275154-A1 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition SAKAYORI KATSUYA 2008-11-06 US disclosed
US-7410746-B2 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition DAI NIPPON PRINTING CO., LTD. (JP) 2008-08-12 US disclosed
US-4675370-A Resin systems derived from benzocyclobutene-alkyne imide monomers UNIVERSITY OF DAYTON (US) 1987-06-23 US disclosed
EP-0010994-B1 PROCESS FOR PRODUCING SUBSTITUTED NAPHTHALIC ACID COMPOUNDS BRENT CHEMICALS INTERNATIONAL PLC (GB) 1983-04-20 EP disclosed
US-4380619-A POLYBENZOTHIAZOLES; N-HETEROCYCLIC POLYMERS; SOLUBILITY; HEAT RESISTANCE; AIRCRAFT; AEROSPACE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1983-04-19 US disclosed
US-4371694-A DENITRATION, AMINATION BRENT CHEMICALS INTERNATIONAL LIMITED (GB) 1983-02-01 US disclosed
WO-1980000963-A1 AROMATIC COMPOUNDS AND THEIR MANUFACTURE BRENT CHEMICALS INT (GB) 1980-05-15 WO disclosed
EP-0010994-A1 Process for producing substituted naphthalic acid compounds BRENT CHEMICALS INTERNATIONAL PLC (GB) 1980-05-14 EP disclosed
US-4172202-A Process for the preparation of 4-amino-1,8-naphthalimides HOECHST AKTIENGESELLSCHAFT (DE) 1979-10-23 US disclosed
US-4151358-A Ethynyl-substituted bis-naphthalimides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1979-04-24 US disclosed
US-4086248-A Ethynyl-substituted aromatic anhydrides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1978-04-25 US disclosed
US-4081446-A DEHALOGENATION, AMMONIATION HOECHST AKTIENGESELLSCHAFT (DT) 1978-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250044298-A1 Oligosaccharide-Fluorescent Marker, and Preparation Method and Use thereof FUCA2, FUT5, OSTC CTSB 3460/4885TDP1 4709/4885ALDH1A1 693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.