Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430709 | 0.85 | LOXL2 (0.58) | SMN1; SMN2MAPTRAB9ANPC1CA1 | |
| SCHEMBL2145311 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2HTTMAPTL3MBTL1RAB9A | |
| SCHEMBL11988605 | 0.81 | SMN1; SMN2 (0.69) | SMN1; SMN2HTTMAPTL3MBTL1RAB9A | |
| SCHEMBL4712796 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTMAPTL3MBTL1RAB9A | |
| SCHEMBL7746905 | 0.80 | CA1 (0.79) | SMN1; SMN2HTTMAPTRAB9AALDH1A1 | |
| SCHEMBL25232330 | 0.80 | SMN1; SMN2 (0.77) | SMN1; SMN2HTTMAPTL3MBTL1RAB9A | |
| SCHEMBL7322209 | 0.80 | HTT (0.73) | SMN1; SMN2HTTMAPTL3MBTL1RAB9A | |
| SCHEMBL2940862 | 0.80 | SMN1; SMN2 (0.77) | SMN1; SMN2HTTMAPTL3MBTL1RAB9A | |
| SCHEMBL28120177 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2HTTMAPTL3MBTL1RAB9A | |
| SCHEMBL9125949 | 0.79 | HTT (0.67) | SMN1; SMN2HTTMAPTL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114899-A2 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | Firmenich S.A. (CH) | 2009-11-11 | — | — | EP | claimed |
| WO-2008093272-A2 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | FIRMENICH SA (CH) | 2008-08-07 | — | — | WO | claimed |
| EP-2114899-A2 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | Firmenich S.A. (CH) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008093272-A2 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | FIRMENICH SA (CH) | 2008-08-07 | — | — | WO | disclosed |