Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 4/20 | 0.81 |
| ▸ | MMP13 | P45452 | 4/20 | 0.81 |
| ▸ | MMP2 | P08253 | 2/20 | 0.64 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440725 | 1.00 | MMP12 (0.81) | MMP12MMP13MMP2ADAM17 | |
| SCHEMBL6455265 | 0.93 | MMP13 (0.74) | MMP12MMP13MMP2 | |
| SCHEMBL4057638 | 0.93 | MMP12 (0.70) | MMP12MMP13MMP2ADAM17 | |
| SCHEMBL4057642 | 0.93 | MMP12 (0.70) | MMP12MMP13MMP2ADAM17 | |
| SCHEMBL4056797 | 0.92 | MMP12 (0.69) | MMP12MMP13MMP2ADAM17 | |
| SCHEMBL4056790 | 0.92 | MMP12 (0.69) | MMP12MMP13MMP2ADAM17 | |
| SCHEMBL6675782 | 0.92 | MMP12 (0.69) | MMP12MMP13MMP2ADAM17 | |
| SCHEMBL4050725 | 0.91 | MMP12 (0.71) | MMP12MMP13MMP2ADAM17 | |
| SCHEMBL4050722 | 0.91 | MMP12 (0.71) | MMP12MMP13MMP2ADAM17 | |
| SCHEMBL4052468 | 0.91 | MMP12 (0.67) | MMP12MMP13MMP2ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397137-B1 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | EP | claimed |