SCHEMBL4440724

SCHEMBL4440724

CC(C)(C)c1ccc(C(OP(O)F)c2ccc(C(C)(C)C)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
TRPV1 Q8NER1 2/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
ACHE P22303 1/20 0.30
NPC1 O15118 1/20 0.30
PLA2G1B P04054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30967276 0.87 ALDH1A1 (0.36) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL9278616 0.87 ALDH1A1 (0.36) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL10413837 0.86 SHBG (0.34) CYP3A4
SCHEMBL7736385 0.86 ALDH1A1 (0.35) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL10583887 0.85 ALDH1A1 (0.33) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL9328504 0.84 ALDH1A1 (0.34) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL9356380 0.84 SMN1; SMN2 (0.35) ALDH1A1
SCHEMBL10334924 0.83 ALDH1A1 (0.33) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL9355773 0.81 HSPA5 (0.36)
SCHEMBL9356457 0.80 L3MBTL1 (0.32) CYP1A2CYP3A4CYP2C9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 EP claimed
EP-0301355-B1 Aqueous aryl fluorophosphite suspension ETHYL CORP (US) 1993-12-29 EP claimed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 US claimed
EP-0416321-A1 Crystalline polyolefin composition Chisso Corporation (JP) 1991-03-13 EP claimed
US-4958034-A DISCOLORATION INHIBITION; REACTION OF OLEFIN AND MALEIC ANHYDRIDE IN ARYLFLUOROPHOSPHITE PRESENCE ETHYL CORPORATION (US) 1990-09-18 US claimed
US-4867907-A POLYMER STABILIZERS ETHYL CORPORATION (US) 1989-09-19 US claimed
EP-1384752-B1 INSULATED ELECTRIC WIRE YAZAKI CORP (JP) 2009-10-28 EP disclosed
US-6894227-B2 Insulated electric wire YAZAKI CORPORATION (JP) 2005-05-17 US disclosed
US-20040168820-A1 INSULATED ELECTRIC WIRE YAZAKI CORPORATION (JP) 2004-09-02 US disclosed
EP-1384752-A1 INSULATED ELECTRIC WIRE YAZAKI CORPORATION (JP) 2004-01-28 EP disclosed
EP-0622404-B1 Crystalline synthetic resin composition containing a group III or IV metal salt of a cyclic organophosphoric ester ASAHI DENKA KOGYO KK (JP) 1998-07-08 EP disclosed
EP-0658556-B1 Piperidine compound and stabilized polymeric material composition containing the same ASAHI DENKA KOGYO KK (JP) 1997-05-28 EP disclosed
US-5455347-A Di(2,2,6,6-tetramethylpiperidyl)-diaminotriazine derivatives as polymeric stabilizers giving heat, light and weather resistance ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1995-10-03 US disclosed
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 EP disclosed
EP-0622404-A1 Crystalline synthetic resin composition containing a group III or IV metal salt of a cyclic organophosphoric ester ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1994-11-02 EP disclosed
US-5342868-A Containing alkali metal salt and polyvalent metal salt of a cyclic organophosphoric ester ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1994-08-30 US disclosed
EP-0301355-B1 Aqueous aryl fluorophosphite suspension ETHYL CORP (US) 1993-12-29 EP disclosed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 US disclosed
EP-0416321-A1 Crystalline polyolefin composition Chisso Corporation (JP) 1991-03-13 EP disclosed
US-4867907-A POLYMER STABILIZERS ETHYL CORPORATION (US) 1989-09-19 US disclosed