SCHEMBL4440836

SCHEMBL4440836

Cc1cn([C@@]2(C(F)(F)F)CC[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.47
POLA1 P09884 2/20 0.47
POLD1 P28340 1/20 0.47
P2RY6 Q15077 9/20 0.42
P2RY2 P41231 3/20 0.41
P2RY4 P51582 2/20 0.41
TK1 P04183 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26119686 0.84 POLB (0.48) POLBPOLA1POLD1P2RY6P2RY2
SCHEMBL599227 0.82 POLB (0.47) POLBPOLA1POLD1P2RY6P2RY2
SCHEMBL29625276 0.81 POLB (0.53) POLBPOLA1POLD1P2RY6P2RY2
SCHEMBL30583147 0.79 POLB (0.51) POLBPOLA1POLD1P2RY6P2RY2
SCHEMBL7240891 0.78 POLB (0.52) POLBPOLA1POLD1P2RY6P2RY2
SCHEMBL9392106 0.78 POLA1 (0.51) POLBPOLA1POLD1P2RY6P2RY2
SCHEMBL29538414 0.78 POLB (0.51) POLBPOLA1POLD1P2RY6P2RY2
SCHEMBL5026296 0.78 POLB (0.51) POLBPOLA1POLD1P2RY6P2RY2
SCHEMBL5409945 0.76 POLB (0.51) POLBPOLA1POLD1P2RY6P2RY2
SCHEMBL29723202 0.76 POLB (0.51) POLBPOLA1POLD1P2RY6P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2126132-A2 METHODS FOR RAPID FORESNSIC DNA ANALYSIS Ibis Biosciences, Inc. (US) 2009-12-02 EP disclosed
WO-2008104002-A2 METHODS FOR RAPID FORENSIC DNA ANALYSIS IBIS BIOSCIENCES, INC. (US) 2008-08-28 WO disclosed
WO-2004053076-A2 METHODS FOR RAPID DETECTION AND IDENTIFICATION OF BIOAGENTS FOR ENVIRONMENTAL AND PRODUCT TESTING ISIS PHARMACEUTICALS, INC. (US) 2004-06-24 WO disclosed