Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.48 |
| ▸ | POLD1 | P28340 | 1/20 | 0.48 |
| ▸ | P2RY6 | Q15077 | 8/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.39 |
| ▸ | TK1 | P04183 | 3/20 | 0.38 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.38 |
| ▸ | DTYMK | P23919 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440836 | 0.84 | POLB (0.47) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL599227 | 0.84 | POLB (0.47) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL29625276 | 0.82 | POLB (0.53) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL30583147 | 0.80 | POLB (0.51) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL2633815 | 0.79 | LMNA (0.41) | POLBTK1 | |
| SCHEMBL7240891 | 0.78 | POLB (0.52) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL5285301 | 0.77 | POLB (0.48) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL29538414 | 0.77 | POLB (0.51) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL5026296 | 0.77 | POLB (0.51) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL9392106 | 0.76 | POLA1 (0.51) | POLBPOLA1POLD1P2RY6P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230332197-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP | ILLUMINA, INC. | 2023-10-19 | — | — | US | disclosed |
| WO-2023192900-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP USEFUL IN SEQUENCING BY SYNTHESIS | ILLUMINA SINGAPORE PTE. LTD. (SG) | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230332197-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP | NT5C3B, NSUN2, DUT | POLB 42/4885POLA1 229/4885POLD1 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.